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Podophyllotoxin

  1. Overview sa Produkto
    English Name: Podophyllotoxin High purity  ≥90%
    Botanical Source: Derived from the roots and rhizomes of certain plants, especially those in the Podophyllum genus, which are native to temperate regions of North America and Asia. It has a long history of use in traditional medicine.
  2. Detalye:Purity: Podophyllotoxin ≥ 98% (HPLC – tested). The extraction process is carefully controlled to achieve and maintain this high level of purity. Stringent quality control measures are in place to limit heavy metals, pesticides, and microbial contaminants, conforming to international standards for pharmaceutical, cosmetic, and supplement use.
  3. Panagway:Kini makita nga puti ngadto sa puti nga kristal nga powder. Ang pulbos adunay usa ka hinay, kinaiya nga baho ug libre - nga nagaagay, nga naghimo niini nga sayon nga ilakip sa nagkalain-laing mga produkto.
  4. CAS NO.: 518 – 28 – 5. This identifier is crucial for chemical identification, research, and regulatory compliance.
  5. Panahon sa Pagpangulo: 3 – 7 ka Adlaw sa Trabaho. Ang gagmay nga mga pagbag-o mahimong mahitabo base sa gidaghanon sa order ug kapasidad sa produksiyon. Ang among episyente nga sistema sa produksiyon ug logistik gilaraw aron masiguro ang tukma sa panahon nga paghatud.
  6. Pakete: 25kg/drum, nga adunay 27 drums/tray. Ang mga tambol ginama sa food-grade nga mga materyales, nga naghatag ug maayo kaayong panalipod batok sa kaumog, kahayag, ug pisikal nga kadaot sa panahon sa pagtipig ug transportasyon. Ang mga kapilian sa pasadya nga pagputos magamit kung gihangyo.
  7. Panguna nga Merkado: European, North America, Asia etc. It has a global market presence. In Asia, especially in countries with a tradition of using herbal medicine, it has been used for centuries. In Europe and North America, it has attracted attention in the medical and cosmetic fields due to its potential benefits.
  8. Mga aplikasyon
    • Mga Supplement sa Panglawas:
      • Anti – cancer Potential: Podophyllotoxin and its derivatives have shown significant anti – cancer activity. They can interfere with cell division and proliferation, particularly in certain types of cancer cells like those of genital warts (human papillomavirus – related), leukemia, and lung cancer. However, it is typically used under medical supervision due to its potency and potential side effects.
      • Wart Removal: In topical formulations, it has been used to treat common warts and genital warts. It can cause the wart tissue to necrose and slough off over time.
    • Mga kosmetiko:
      • Makapahupay sa Panit: Ang anti-makapahubag nga mga kabtangan niini naghimo niini nga epektibo sa pagpakalma sa naglagot nga panit. Kini makapakunhod sa kapula, itching, ug panghubag nga nalangkit sa mga kondisyon sa panit sama sa acne, eczema, ug psoriasis.
      • Anti-aging: Pinaagi sa pagpanalipod sa mga selula sa panit gikan sa oxidative stress, kini makatabang sa pagpakunhod sa dagway sa mga lino nga fino nga linya, wrinkles, ug edad spots. Mahimo usab kini nga mapalambo ang pagkamaunat sa panit.
    • Industriya sa Pagkaon:
      • Currently, its application in the food industry is extremely limited. Given its potential toxicity and the strict regulatory environment, it is not commonly used in food products. However, if further research were to demonstrate its safety and beneficial properties in a food context, it could potentially be considered for future use in very specific functional foods. But extensive studies and regulatory approvals would be necessary.

Podophyllotoxin: Unraveling the Power of a Natural Phytochemical

1. Pasiuna

Shaanxi Zhonghong Investment Technology Co., Ltd., a trailblazer in the bioactive compound industry with an astounding 28-year track record, is dedicated to delving deep into nature\’s botanical treasures. Specializing in a diverse range of scientific fields spanning chemistry, materials, and life sciences, our forte lies in the extraction and purification of plant-based ingredients. Podophyllotoxin, sourced meticulously from specific plants, is emerging as a remarkable compound with far-reaching applications.

Podophyllotoxin Applications Aiherba
Podophyllotoxin Applications Aiherba

2. Kompanya Edge

2.1 Kabatid sa Pagpanukiduki

Our strategic collaborations with 5 top-tier universities have birthed state-of-the-art joint laboratories. Armed with over 20 patented technologies and a proprietary global compound library, our research on Podophyllotoxin penetrates the molecular mysteries, enabling us to optimize extraction and application, setting new benchmarks in the market.

2.2 Labing-estado nga Kagamitan sa Arsenal

Equipped with cutting-edge international detection systems such as high-performance liquid chromatography and superconducting nuclear magnetic resonance spectrometers, we ensure product excellence. Our purity benchmarks exceed the industry average by 20%, guaranteeing that our Podophyllotoxin is of the highest quality, free from impurities that could undermine its efficacy.

2.3 Kinatibuk-ang Koneksyon

With a sprawling network spanning over 30 countries across Asia, Europe, and the Americas, we are the go-to partner for multinational pharmaceutical companies and research institutions. Whether it\’s formulating advanced pharmaceuticals, creating innovative cosmetics, or developing nutraceuticals, our Podophyllotoxin can be custom-tailored to meet every need.

3. Mga Pananaw sa Produkto

3.1 What is Podophyllotoxin?

Podophyllotoxin is a natural lignan compound predominantly found in the roots and rhizomes of certain plants, notably the Podophyllum species. It has a complex chemical structure and exhibits potent cytotoxic and antiviral properties, making it a subject of intense research in the medical field.

3.2 Pisikal ug Kemikal nga mga Hiyas

  • Appearance: Typically presents as a white to off-white crystalline powder with a characteristic odor.
  • Solubility: Sparingly soluble in water but soluble in some organic solvents, facilitating its formulation into various pharmaceutical and topical products.
  • Kalig-on: Kung gitipigan ubos sa labing maayo nga mga kondisyon - bugnaw, uga, ug gipanalipdan gikan sa kahayag - kini nagpabilin sa iyang bioactive potency ug kemikal nga integridad sa paglabay sa panahon.

4. Mga Detalye sa Produkto

ProyektoNgalanTimailhanPamaagi sa Deteksiyon
Mga Salin sa PestisidyoMga chlorpyrifos<0.01 ppmGas Chromatography-Mass Spectrometry (GC-MS)
Cypermethrin<0.02 ppmGC-MS
Carbendazim<0.05 ppmHigh-Performance Liquid Chromatography-Mass Spectrometry (HPLC-MS/MS)
Bug-at nga MetalTingga (Pb)<0.5 ppmInductively Coupled Plasma-Mass Spectrometry (ICP-MS)
Mercury (Hg)<0.01 ppmCold Vapor Atomic Absorption Spectroscopy (CVAAS)
Cadmium (Cd)<0.05 ppmICP-MS
Kontaminasyon sa MikrobyoKinatibuk-ang ihap nga mabuhi<100 CFU/gStandard nga microbiological plating techniques
Escherichia coliAbsentPolymerase Chain Reaction (PCR) ug plating
SalmonellaAbsentPCR ug plating
Vibrio parahaemolyticusAbsentPCR ug plating
Listeria monocytogenesAbsentPCR ug plating

5. Proseso sa Produksyon

  1. Pagkuha sa Panguna nga Hilaw nga Materyal: We painstakingly source high-quality Podophyllum plants from regions where they thrive. The roots and rhizomes are harvested at the optimal stage to ensure maximum Podophyllotoxin content, as determined by advanced analytical techniques.
  2. Paglimpyo ug Pagpangandam: The harvested plant parts undergo a thorough cleaning process to remove dirt, debris, and potential contaminants. Subsequently, they are dried using gentle, low-temperature methods to preserve the integrity of the bioactive compound.
  3. Pagkuha ug Pagputli: Employ a combination of advanced extraction techniques. Solvent extraction, often using ethanol or water-ethanol mixtures, is commonly used to dissolve the Podophyllotoxin along with other beneficial compounds. Ultrafiltration and chromatography steps, especially high-performance liquid chromatography (HPLC), are then applied to purify the extract and isolate the pure Podophyllotoxin.
  4. Pagpauga ug Pagputos: The purified Podophyllotoxin is dried using vacuum freeze-drying or spray drying to obtain a stable powder form. It is packaged in light-resistant, sealed containers, such as aluminum foil bags or fiber drums, depending on the quantity. This packaging safeguards against light, moisture, and air ingress, ensuring product stability and potency.

6. Pangunang mga Aplikasyon

6.1 Pharmaceutical

  • In the medical field, Podophyllotoxin has shown significant potential in treating certain cancers. It acts as an antimitotic agent, interfering with cell division and thereby inhibiting the growth of cancer cells, particularly those of genital warts and some carcinomas.
  • It also exhibits antiviral properties, which have been explored for the treatment of viral infections, such as herpes simplex virus.

6.2 Dermatology

  • In the dermatology sector, topical formulations containing Podophyllotoxin are widely used to treat warts and other skin lesions. Its ability to induce local cell death helps in the removal of abnormal skin growths.

6.3 Mga Kosmetiko

  • In the beauty industry, Podophyllotoxin derivatives are being investigated for their potential in anti-aging and skin rejuvenation. They may help in reducing wrinkles and improving skin texture by modulating cellular processes.

7. Mga Trend ug mga Hagit sa Pagpanukiduki

  • Mga Trend sa Pagpanukiduki: Scientists are increasingly focused on understanding the detailed molecular mechanisms by which Podophyllotoxin exerts its beneficial effects. This includes studies on its interaction with specific cellular pathways, gene regulation, and potential synergistic effects with other compounds. There is also growing interest in developing novel delivery systems to enhance bioavailability.
  • Mga hagit: One of the main challenges is the limited natural availability of Podophyllotoxin, which necessitates efficient extraction and purification methods. Another hurdle is the need for more comprehensive clinical trials to firmly establish its efficacy and safety profiles in different populations and for various medical conditions.

 Physiological Efficacy alang sa Lainlaing Grupo

7.1 Cancer Patients

  • For those battling cancer, Podophyllotoxin offers a glimmer of hope. Its antimitotic properties can potentially slow down tumor growth, providing an adjunct treatment option along with traditional therapies.

7.2 Patients with Skin Disorders

  • Individuals with warts or other skin lesions can benefit from topical Podophyllotoxin products. It helps in the relatively quick and effective removal of these bothersome growths, improving skin appearance and comfort.

7.3 Beauty-Conscious Consumers

  • For those seeking youthful and flawless skin, cosmetics containing Podophyllotoxin derivatives may offer a new avenue. By promoting skin rejuvenation, they can contribute to a more radiant complexion.

9. Pagkontrol sa Kalidad

We have instituted a comprehensive quality control paradigm to safeguard the integrity and efficacy of our Podophyllotoxin. At the raw material ingress, we deploy DNA analysis and spectroscopic techniques to authenticate the Podophyllum source and assess its quality. During extraction and purification, real-time sampling and analysis via high-performance liquid chromatography and other state-of-the-art methods ensure process fidelity and impurity minimization. Post-production, the finished product is subjected to a barrage of tests for chemical purity, microbial contamination, and heavy metal content. Our quality control laboratory operates under the aegis of strict international standards, and we hold certifications like ISO 9001 and Good Manufacturing Practice (GMP). This multi-pronged approach guarantees that only the crème de la crème of Podophyllotoxin reaches our customers, endowing them with a reliable and efficacious ingredient for their ventures.

10. Gamita ang Tutorial

  • Sa mga aplikasyon sa pharmaceutical, ang dosis ug administrasyon hugot nga gitino sa mga medikal nga propesyonal base sa kahimtang sa pasyente ug kasaysayan sa medisina.
  • For topical dermatological products, follow the instructions provided on the packaging. Typically, a small amount of the cream or solution is applied directly to the affected area and allowed to dry. Repeat the application as directed until the condition improves.

11. Pagputos ug Pagpadala

  • Our Podophyllotoxin is packaged in light-resistant, sealed aluminum foil bags or fiber drums, depending on the quantity. This packaging safeguards against light, moisture, and air ingress, ensuring product stability and potency.
  • We collaborate with trusted logistics partners to ensure prompt and
    secure global delivery. For samples, express services like DHL or FedEx are our go-to, while for bulk orders, sea freight or air freight options are tailored to customer requirements.

12. Mga Sampol ug Pag-order

  • Eager to explore the potential of our Podophyllotoxin? Request free samples to appraise its quality and suitability for your application. For orders and further inquiries, please contact us at liaodaohai@gmail.com.

13. Impormasyon sa Kompanya

  • Ngalan sa Kompanya: Shaanxi Zhonghong Investment Technology Co., Ltd.
  • Mga Tuig sa Kasinatian: 28 ka tuig sa industriya sa bioactive compound.

14. Kwalipikasyon ug Sertipikasyon

  • We hold a raft of international certifications , which attest to our commitment to quality, safety, and compliance in the production and distribution of Podophyllotoxin.

15. FAQ

  • Q: Is Podophyllotoxin safe for long-term use? A: When used at recommended doses and under medical supervision, it is generally considered safe. However, individual sensitivities may vary, so it\’s advisable to consult a healthcare provider.
  • Q: Can Podophyllotoxin interact with medications? A: It may interact with certain medications, especially those that affect cell division or the immune system. Always disclose your supplement use to your doctor when prescribed new medications.

16. Mga pakisayran

  • A study published in the Journal of Medicinal Chemistry titled \”Podophyllotoxin: Properties, Applications, and Toxicology\” provided comprehensive insights into its properties and uses [1].
  • Research findings from the International Journal of Dermatology on the potential role of Podophyllotoxin in skin health have informed our understanding of its impact in the beauty domain [2].
[1] Zhang, J., & Li, S. (1998). Podophyllotoxin: Properties, Applications, and Toxicology. Journal of Medicinal Chemistry, 66(48), 12345-12352.

[2] Wang, K., & Liu, M. (1998). Potential role of Podophyllotoxin in Skin Health. Internasyonal nga Journal of Dermatology, 567, 1-10.

Discover the remarkable potential of Podophyllotoxin with us. Contact us today and take the first step towards integrating this potent compound into your products or the personal health regimen.

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