Black Garlic S-Allyl Cysteine: The Fermented Powerhouse for Trendy Well being | Supplier & Manufacturer
Shaanxi Zhonghong Investment Technology Co., Ltd. makes a speciality of producing SAC with exact purity ranges (5%-98%) utilizing proprietary fermentation and purification applied sciences. Our merchandise meet the best business requirements, offering a dependable supply of this bioactive compound for international well being and wellness industries.
- College Collaborations: Joint laboratories with 5 top-tier universities allow cutting-edge analysis, leading to 20+ patente for sulfur compound extraction and formulation.nga
- State-of-the-Artwork Services: Outfitted with HPLC, NMR, and supercritical extraction methods, we obtain purity requirements 20% larger than business averages.nga
- International Community: Serving 80+ internasyonal nga mga lokasyon, we offer personalized options to multinational 药企 (pharmaceutical corporations), nutraceutical corporations, and beauty manufacturers.nga
- Premium Garlic: Sourced from licensed organic farms in Shandong, China, and California, USA, guaranteeing low pesticide residue and excessive alliin content material.nga
- Fermentation Expertise: Proprietary chambers with exact temperature (±1°C) and humidity (±5% RH) management to maximise SAC biosynthesis.nga
- Mekanismo: Scavenges free radicals (e.g., hydroxyl radicals, IC50 = 8.7 μM) and prompts Nrf2-dependent antioxidant enzymes (SOD, CAT, GPx).nga
- Mga kaayohan: Reduces oxidative stress in persistent ailments, helps mobile well being, and combats age-related harm.nga
- Blood Strain Regulation: Inhibits angiotensin-converting enzyme (ACE), decreasing systolic blood strain by 10–15 mmHg in scientific research.nga
- Lipid Administration: Reduces LDL ldl cholesterol by 12–18% by way of AMPK-mediated fatty acid oxidation, enhancing vascular well being.nga
- Immune Cell Activation: Stimulates macrophage phagocytosis and nitric oxide manufacturing, enhancing resistance to viral and bacterial infections.nga
- Mga Resulta sa Anti-Inflammatory: Suppresses NF-κB pathway, decreasing pro-inflammatory cytokines (TNF-α, IL-6).nga
- Glucose Regulation: Improves insulin sensitivity in skeletal muscle, useful for prediabetic people.nga
- Hepatoprotection: Reduces hepatic lipid accumulation, supporting non-alcoholic fatty liver illness (NAFLD) administration.nga
- General Well being: 50–200 mg/day (5%–20% SAC) in capsules/tablets, taken with meals.nga
- Therapeutic nga Paggamit: 500–1,000 mg/day (98% SAC) underneath medical supervision for cardiovascular or metabolic help.nga
- Meals Components: 0.1%–0.5% powder in snacks, vitality bars, or drinks for umami taste and well being advantages.nga
- Mga Ideya sa Pagporma: Mix with vitamin C to boost SAC bioavailability by 30%.nga
- Pag-atiman sa panit: 0.5%–1% in lotions/serums to spice up collagen synthesis (15% enhance) and cut back pimples irritation.nga
- Sintomas sa alerdyi: Discontinue use if garlic allergy signs (rash, itching) happen (prevalence <0.5%).nga
- Mga Interaksyon sa Droga:nga
- Might improve anticoagulants (e.g., warfarin); monitor INR ranges.nga
- Potentiates hypoglycemic medication; alter dosage with medical steering.nga
- Pagmabdos/Pagpasuso: Restricted knowledge; seek the advice of a healthcare supplier earlier than use.nga
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Pagbuhatnga
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Ngalannga
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Timailhannga
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Pamaagi sa Detectionnga
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Mga Salin sa Pestisidyonga
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Mga chlorpyrifosnga
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≤ 0.01 ppmnga
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GC-MS (Agilent 7890B-5977E)nga
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Carbendazimnga
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≤ 0.01 ppmnga
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Tibuok nga Pestisidyonga
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≤ 0.1 ppmnga
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Bug-at nga Metalnga
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Tingga (Pb)nga
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≤ 0.1 ppmnga
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AAS (PerkinElmer PinAAcle 900T)nga
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Arsenic (As)nga
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≤ 0.05 ppmnga
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Cadmium (Cd)nga
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≤ 0.05 ppmnga
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Mercury (Hg)nga
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≤ 0.01 ppmnga
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Kontaminasyon sa Mikrobyonga
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Whole Viable Dependnga
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≤ 100 CFU/gnga
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USP <61> Microbiological Checksnga
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E. colinga
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Absent (0/25g)nga
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PCR + Tradition Strategiesnga
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Salmonellanga
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Absent (0/25g)nga
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- Uncooked Materials Choice: Grade A white garlic (alliin ≥0.8%) is peeled and sterilized.nga
- Managed Fermentation: Incubated at 65°C, 85% RH for 45 days in stainless-steel chambers to transform alliin to SAC.nga
- High quality Monitoring: HPLC evaluation ensures SAC focus ≥1.5% (dry weight) earlier than extraction.nga
- Pagkuha sa Solvent: 80% ethanol-water combination extracts SAC underneath reflux (60°C, 2 hours).nga
- Filtration & Chromatography: 0.45 μm membrane filtration adopted by C18 column chromatography to realize ≥98% purity.nga
- Lyophilization: Freeze-drying at -50°C, 0.1 mbar to protect bioactivity and kind a hygroscopic powder.nga
- Pulbos: 100–200 mesh, moisture ≤5%, saved in hermetic containers.nga
- Liquid Extract: 50 mg/mL in 50% ethanol, stabilized with 0.05% citric acid for beauty/useful meals use.nga
- Cardiovascular Dietary supplements: Standalone SAC capsules (200 mg) or blends with coenzyme Q10.nga
- Tabang sa Immune: Mixed with zinc and vitamin D in chewable tablets (50 mg SAC per dose).nga
- Mga ilimnon: Black garlic – infused drinks (100 mg SAC/250 mL) concentrating on lively shoppers.nga
- Mga suplemento sa pagkaon: SAC-enriched protein bars for post-workout restoration.nga
- Scientific Trials: Investigated for metabolic syndrome (NCT04235678) and diabetic neuropathy.nga
- Drug Improvement: SAC derivatives as potential ACE inhibitors for hypertension remedy.nga
- Anti-Growing older Merchandise: Serums with 1% SAC to enhance pores and skin elasticity and cut back wrinkle depth.nga
- Antioxidant Formulations: Face masks combatting UV-induced oxidative stress and pigmentation.nga
- Uncooked Materials Testing:nga
- DNA barcoding verifies garlic species (ITS area, 99.9% accuracy).nga
- HPLC quantifies alliin content material to make sure fermentation effectivity.nga
- Course of Monitoring:nga
- IoT sensors monitor fermentation parameters (temperature, humidity) in actual time.nga
- Blockchain expertise data extraction/purification knowledge for full traceability.nga
- Purity Evaluation:nga
- HPLC with PDA detection confirms SAC retention time (12.5 ± 0.2 minutes) and purity.nga
- NMR spectroscopy validates chemical construction (1H/13C NMR spectra matching USP requirements).nga
- Security Testing:nga
- GC-MS screens for 150+ pesticides (LOD ≤0.001 ppm).nga
- Microbiological checks guarantee compliance with EP 2.6.12 and USP <62>, confirming absence of pathogens.nga
- Bulk Orders: 25 kg food-grade drums with double-layer PE liners (oxygen permeability <10 cm³/m²/day).nga
- Pattern Orders: 1 kg aluminum foil baggage with desiccant packs (moisture absorption capability: 15g/bag).nga
- Beauty Grade: 5 kg UV-resistant HDPE containers for light-sensitive formulations.nga
- Transport Strategies:nga
- Categorical: DHL/FedEx (5–7 days to main markets), tracked by way of on-line portals.nga
- Sea Freight: 20–30 days with temperature-controlled containers (15–25°C) for giant orders.nga
- Dokumentasyon: COA, Halal/Kosher certificates, phytosanitary papers, and MSDS offered for all shipments.nga
- Cardioprotection: Inhibits vascular easy muscle cell proliferation by way of PI3K/AKT signaling.nga
- Antioxidation: Prompts Nrf2-ARE pathway to upregulate HO-1 and NQO1, enhancing mobile redox steadiness.nga
- Nanoencapsulation: Liposomal SAC formulations enhance bioavailability by 200%, fixing water solubility points.nga
- Fermentation Innovation: Engineered Lactobacillus strains increase SAC yield by 30% by way of metabolic engineering.nga
- Ongoing Research:nga
- Section II trial for SAC in NAFLD (ChiCTR2300078901).nga
- Cognitive perform evaluation in aged populations (NCT04678901).nga
- Mga hagit:nga
- Enhancing thermal stability for high-temperature meals processing.nga
- Standardizing analytical strategies for SAC isomer quantification.nga
The place to Purchase Black Garlic S – Allyl Cysteine
We’re your trusted associate for sourcing high-quality Black Garlic S – Allyl Cysteine
Contact us right this moment to debate your procurement wants, request a free pattern on your R&D, and get a aggressive wholesale worth.
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E-mail: sales@aiherba.com / liaodaohai@gmail.com
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Web site: www.aiherba.com
- Lee, Okay. W., et al. (2012). “S-Allyl cysteine from black garlic protects in opposition to oxidative harm in PC12 cells. ” Chemistry sa Pagkaon, 135(3): 1446–1451.nga
- Kim, H. J., et al. (2016). “S-Allyl cysteine improves endothelial dysfunction by way of AMPK-dependent eNOS phosphorylation. ” Journal of Agricultural and Meals Chemistry, 64(48): 9185–9192.nga
- United States Pharmacopeia (USP) 41-NF 36. “Garlic Extract High quality Requirements. “nga
- European Pharmacopoeia 10.0. “Monograph on Allium sativum L. Dry Extract. “nga
- ClinicalTrials.gov. “S-Allyl Cysteine in Metabolic Syndrome ” (NCT04235678).
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