Bioperine

Bioperine®: The Gold Standard in Bioavailability Enhancement – A Manufacturer’s Guide

1. What is Bioperine®?

Let’s cut through the noise. Bioperine® is not just black pepper extract. It’s a patented, clinically-studied ingredient derived from the fruits of Piper nigrum L. (black pepper) and standardized to contain ≥95% piperine. Think of it as the key that unlocks the full potential of your supplements. Its primary, and most valuable, function is to significantly enhance the bioavailability of other active compounds, making your formulations more effective and efficient.

2. Source, Chemistry & Specifications

• Tinubdan: Sourced from the dried fruits of Piper nigrum L.

• Key Bioactive: Piperine (Standardized to ≥95%).

• Kemikal nga Profile:

  • CAS No.: 94-62-2

  • MF: C₁₇H₁₉NO₃

  • MW: 285.34 g/mol

  • EINECS: 202-348-0

• Panagway: Off-white to pale yellow crystalline powder.

• Solubility: Soluble in ethanol and chloroform; sparingly soluble in water.

3. The Zhonghong Standard: Why Our Bioperine® is Best for B2B
Kay nutraceutical ingredients suppliers ug private label supplement manufacturers, consistency and proof are everything. Here’s what defines a premium-grade Bioperine®:

• Key Ingredient & Potency: ≥95% Piperine. This high level of purity is non-negotiable for reliable and potent bioavailability enhancement.

• Proven Efficacy (Compliant Claims):

  • Bioavailability Enhancer: Clinically shown to increase the absorption of various nutrients (e.g., Curcumin, CoQ10, Vitamins, Selenium).

  • Thermogenic Activity: Supports metabolic rate and nutrient utilization.

  • (Note: This product is not intended to diagnose, treat, cure, or prevent any disease. Structure/function claims must be compliant with local regulations).

• Optimal Use Level: Typically used at a 1-5% ratio relative to the active compound it is enhancing (e.g., 5-10mg of Bioperine® per 500mg of Curcumin). Dosage should be finalized based on the specific formulation.

• Origin & Quality: Gikuha gikan sa premium Piper nigrum and processed to meet stringent international standards.

• Aplikasyon: Ideal for incorporation into tablets, capsules, and powder formulations for dietary supplements.

• Target nga mga pormulasyon: Essential for private label supplement manufacturers creating products with high-value actives like turmeric/curcumin, resveratrol, multivitamins, and cognitive health blends.

• Safety & Considerations:

  • Generally Recognized as Safe (GRAS): At recommended levels.

  • Mga Interaksyon sa Droga: May affect the metabolism of certain pharmaceutical drugs by inhibiting cytochrome P450 enzymes and UDP-glucuronylation. Consult a medical expert if formulating for populations on medication.

  • Pagmabdos/Pagpapasuso: Recommended to avoid high doses.

4. Zhonghong Biotech: Your Strategic Ingredient Partner
When you need a reliable bulk botanical extracts partner, you need more than a vendor. You need a technical expert. Shaanxi Zhonghong Investment Technology Co., Ltd. is a certified supplier sa nutraceutical nga sangkap with 28 years of experience in bioactive compound manufacturing.

• Kinauyokan nga Eksperto: We are specialists in the precision extraction and purification of plant-derived actives. Our portfolio is built for B2B:

  • Standardized Botanical Extracts (like Bioperine®)

  • Cosmetic Raw Material Supplier offerings

  • Nutraceutical Ingredients for supplements and functional foods

  • API Intermediates

• Our B2B Value Proposition:

  • Innovation-Driven: 20+ patents and university collaborations ensure we are at the forefront of extraction technology.

  • Quality Assurance: Our investment in HPLC ug NMR spectroscopy guarantees a purity standard that is consistently 20% above common industry specs, providing you with a uncontested competitive edge.

  • Global B2B Network: We supply wholesale botanical extracts ug gipahiangay nga mga solusyon sa OEM herbal extracts partners and major brands in over 80 countries.

5. Technical Insight: Mechanism of Action
Piperine’s primary mechanism is two-fold:

1. Inhibition of Metabolism: It inhibits the enzymes in the liver and intestine (e.g., CYP3A4, UGT) that would normally break down and eliminate other compounds before they enter the bloodstream.

2. Enhancing Absorption: It stimulates amino acid transporters in the intestinal lining and increases blood supply to the GI tract, facilitating greater uptake of co-administered supplements.

6. Uncompromising Quality Control: The COA
Our Quality Control is your formulation’s insurance policy. Every batch is rigorously tested.

Certificate of Analysis (COA) Summary – Bioperine® (≥95% Piperine)

7. Advanced nga Proseso sa Produksyon
Our GMP-compliant process ensures unmatched purity:

1. Pagkuha ug Pag-andam: Selection and cleaning of premium Piper nigrum mga prutas.

2. Pagkuha: Solvent extraction optimized for maximum piperine yield.

3. Pagsala ug Konsentrasyon: Removal of impurities and concentration of the extract.

4. Crystallization & Purification: Further refinement to achieve the ≥95% purity benchmark.

5. Standardisasyon: Precise adjustment to meet the exact specification.

6. Pagpauga ug Paggaling: Conversion into a fine, free-flowing powder.

7. Pagpagawas sa QC: The batch is only released after passing all critical quality parameters.

8. Application in Nutraceutical Formulations
This ingredient is a cornerstone for effective supplement design. Its primary application is in:

• Enhanced Absorption Formulas: Curcumin supplements, multivitamins, coenzyme Q10, resveratrol, and antioxidant blends.

• Weight Management Products: Leveraging its mild thermogenic properties.

• Sports Nutrition: To improve the uptake of amino acids and other performance nutrients.

9. B2B Packaging & Logistics

• Pagputos: Standard 25kg/fiber drum with double polyethylene liners. Customized packaging available for pakyaw ug bulto mga order.

• Pagtipig: Store in a cool, dry place away from strong light.

• Kinabuhi sa estante: 24 months when stored correctly.

• Logistics: We handle global shipping and all export documentation (COA, MSDS, Certificate of Origin) for seamless delivery to OEM partners worldwide.

10. Partner with Us for Your Bulk Ingredient Needs
Zhonghong isn’t just a tigsuplay; we’re your innovation partner. We provide:

• Competitive Bulk Pricing: Get a direct presyo sa pabrika for high-volume orders.

• Customization & OEM: Among gitanyag OEM herbal extracts ug gipahiangay nga mga solusyon tailored to your specific formulation requirements.

• Technical Support: Leverage our 28 years of expertise for your product development.

Contact Us for a Quote or to Request a Sample!

• Web: www.aiherba.com

• Email: sales@aiherba.com; liaodaohai@gmail.com

• Keywords: Bioperine supplier, bulk piperine, nutraceutical ingredients supplier, cosmetic raw material supplier, wholesale botanical extracts, private label supplement manufacturer, OEM herbal extracts, bulk organic ingredients.

11. FAQ for B2B Clients

• Q: What is your Minimum Order Quantity (MOQ) for bulk orders?
  A: Contact us for specific MOQ details. We offer flexible terms for pakyaw ug bulto partners.

• Q: Can you provide custom standardization for private label?
  A: Absolutely. As an OEM herbal extracts partner, we specialize in gipahiangay nga mga solusyon to meet your specific product specs.

• Q: Do you offer technical documentation and regulatory support?
  A: Yes. We provide full documentation (COA, MSDS) and can support with regulatory data for your market.

• Q: What is the lead time for large orders?
  A: Lead times vary based on order size. We maintain strategic stock for popular items and provide clear timelines for custom productions.

• Q: How do I start the qualification process?
  A: Email us at sales@aiherba.com to request a libre nga sample and discuss your specific needs. Our technical team will guide you through the process.

12. Panapos
In the competitive world of supplement manufacturing, ingredient efficacy is paramount. Bioperine® is a proven, powerful tool to differentiate your products and guarantee customer results. Sourcing from a technically advanced, reliable tiggama is critical. Zhonghong Biotech, with its scientific rigor, proven quality, and global B2B supply capability, is the optimal partner for nutraceutical ingredients suppliers ug pribadong label brands. Contact us today to discuss your project and request a sample.

Mga pakisayran:

• Majeed, M., et al. (1999). Piperine, a bioavailability enhancer. US Patent 5,972,382.

• Shoba, G., et al. (1998). Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Medica, 64(4), 353-356.

• Badmaev, V., et al. (2000). Piperine, an alkaloid derived from black pepper, increases serum response of beta-carotene during 14-days of oral supplementation. Nutrition Research, 20(3), 381-388.

• Johnson, J. J., et al. (2011). Enhancing the bioavailability of resveratrol by combining it with piperine. Molecular Nutrition & Food Research, 55(8), 1169-1176.