Beta Arbutin
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Beta arbutin

β-Arbutin supplier bulk factory Wholesale Extract factory

  1. English Ngalan: β-Arbutin,Beta arbutin
  1. Espesipikasyon
    • sukaranan Pulbos: β-Arbutin ≥ 98% (HPLC)
    • Water-soluble Powder: β-Arbutin ≥ 95% (HPLC), enhanced water solubility pinaagi sa microencapsulation or complexing mga broker; solubility kutob sa 20 g/L at 25°C
  1. Panagway
    • sukaranan Pulbos: Puti hangtod sa puti nga kristal nga pulbos, walay baho
    • Water-soluble Powder: Nindot kaayo, white, free-flowing powder
  1. CAS NO.：497-76-7
  1. Panahon sa pagpanguna: 3 – 7 ka Adlaw sa Trabaho
  1. Pakete
    • 1 kg/bag (aluminum foil bag), 25 kg/drum (double-layer PE bag inside cardboard drum)
  1. Panguna nga Merkado: Asia (China, Japan, South Korea), North America, Europe
  1. Mga Sitwasyon sa Aplikasyon

Panguna nga mga kabtangan

  • Molekular Pagporma: C₁₂H₁₆O₇
  • Pagkamatunaw: Sparingly soluble in water; soluble in nagsingot water, ethanol, and propylene glycol. Water-soluble formulations paghatag mas taas dispersion in aqueous mga programa.
  • yawe Mga kapilian
    • Mga pores ug panit Lightening: Inhibits tyrosinase, an enzyme importante for melanin synthesis, pagpaubos ang hitsura sa itom spots, freckles, and hyperpigmentation.
    • Antioxidant Pag-ehersisyo: Pagtangtang sa mga free radical, pagdepensa pores ug panit mga selula gikan sa oxidative kadaot tungod sa UV radiation and environmental polusyon.
    • Kalig-on: Lig-on ubos acidic mga kahimtang (labing maayo pH 4 – 6); mahimo degrade in alkaline environments or at sobra temperatures (above 60°C).

Mga Sitwasyon sa Aplikasyon

1. Mga kosmetiko & Pribado Pag-atiman

  • Mga pores ug panit Whitening Mga baligya
    • Serum ug Mga lotion: Generally formulated at 3 – 7% focus, used to lighten pores ug panit tone, fade age spots, and even out pores ug panit complexion.
    • Mga sunscreen: Added sa pagtanyag dugang kaluwasan padulong sa UV-induced pigmentation, kasagaran gisagol uban sa lainlain solar – filtering mga broker.
    • Mga maskara sa nawong: Infused in sheet masks or clay masks for intensive brightening therapies.
  • Anti- Pagkatigulang Mga pormulasyon
    • Reduces the formation of age – kauban itom spots and helps pagpreserbar collagen integrity, minimizing ang hitsura sa taas nga kalidad mga strain and wrinkles.

2. Gireseta nga mga tambal

  • Dermatological Mga tambal
    • Gigamit sa topical droga para sa tambal of melasma, submit – inflammatory hyperpigmentation, and lainlain pigmentation mga problema.
    • Sa pipila mga higayon, gilakip ngadto sa sagol therapies with lainlain pores ug panit – lightening mga broker for enhanced efficacy.

3. Praktikal Mga pagkaon & Mga ilimnon

  • Oral Mga suplemento sa pagkaon
    • Capsules or tablets containing β-Arbutin are marketed for inner pores ug panit – brightening mga bentaha, kasagaran gisagol uban sa nutritional nga mga bitamina C and E for synergistic antioxidant resulta.
  • Mga ilimnon
    • Gidugang sa kahalangdon – nakasentro drinks at low concentrations (0.1 – 0.5%) sa pag-advertise heneral pores ug panit kaayohan gikan sa sulod.

4. Industrial Mga katuyoan

  • Tela Negosyo
    • Can be utilized ingon a putli dyeing tabang or mordant, nagsilbi sa to repair putli dyes on mga materyales and imparting landong stability.
  • Mga biopestisidyo
    • Ang uban panukiduki irekomendar β-Arbutin mahimo adunay malumo antifungal properties, making it usa ka posible ingredient in eco – makapahimuot agricultural pest pagdumala baligya.

Deteksiyon Mga estratehiya

  • Sobra – Episyente Liquid Chromatography (HPLC)
    • Column: C18 (250 × 4.6 mm, 5 μm); Cell Seksyon: Acetonitrile – water (15:85, v/v); Stream Maningil: 1.0 mL/min; Detection Wavelength: 280 nm. Used to tukma quantify β-Arbutin sulod nga materyal ug garantiya product purity.
  • Niwang – Layer Chromatography (TLC)
    • A fast screening metodolohiya kay paghuna-huna β-Arbutin in samples, paggamit silica gel plates and usa ka madawat cellular bahin for separation.
  • Mass Spectrometry (MS)
    • Naghatag detalyado mga detalye bahin sa the molecular pagtukod of β-Arbutin, makatabang for confirming product id and detecting impurities.

Suplay & Mga kaayohan

  • Natural Suplay: β-Arbutin mahimong gikuha gikan sa daghan katanoman nagpahinumdom sa bearberry (Arctostaphylos uva – ursi), blueberries, and cranberries, giving it a putli ug klaro - label atraksyon.
  • Delikado Pagka-epektibo: Makahatag a gentler estratehiya sa pores ug panit lightening kon itandi sa some stronger chemical mga broker, naghimo niini angay kay delikado pores ug panit barayti.
  • Pagkadagaya: Mahimong yano gilakip ngadto sa usa ka lainlain of formulations, from cosmetics to may katuyoan mga pagkaon.

Pagsunod sa Regulatoryo

  • China NMPA: Allowed as a katahom ingredient with a kadaghanan focus of seven% (requires seguridad ebalwasyon).
  • EU Katahom Regulation (EC 1223/2009): Authorised nga gamiton in cosmetics, with a focus pugong of seven% in depart – on baligya.
  • US FDA: No partikular restrictions nga gamiton sa mga kosmetiko, bisan pa niana mao ang hilisgutan sa sukaranan seguridad mga lagda kay katahom mga elemento.
Mga kategoriya: , , , ,

Beta Arbutin: Premium Skin Brightening Agent for Cosmetic & Pharmaceutical Applications – Manufacturer & Exporter Guide

1. What is Beta Arbutin?
For cosmetic chemists and product developers seeking a superior skin brightening solution, Beta Arbutin represents the gold standard in tyrosinase inhibition. This pure, single-isomer compound (4-Hydroxyphenyl-β-D-glucopyranoside) is the most effective and stable form of arbutin, specifically designed for high-performance skincare formulations. Unlike mixed alpha/beta extracts, our Beta Arbutin offers predictable results and exceptional formulation stability, making it the preferred choice for professional skincare brands and pharmaceutical applications.

Beta Arbutin
Beta Arbutin

2. Source, Chemistry & Specifications

  • Tinubdan: Synthesized through enzymatic biotransformation of hydroquinone and glucose

  • Chemical Identity: Pure β-anomer of arbutin

  • Kemikal nga Profile:

    • CAS No.: 497-76-7

    • MF: C₁₂H₁₆O₇

    • MW: 272.25 g/mol

    • EINECS: 207-850-3

  • Panagway: White to off-white crystalline powder

  • Solubility: Highly soluble in water (≥50 g/100mL), slightly soluble in ethanol

  • Kaputli: ≥99% (HPLC)

3. The Formulator’s Choice: Why Pure Beta Arbutin Outperforms
Kay B2B clients in cosmetic and pharmaceutical manufacturing, ingredient selection impacts final product efficacy and market success:

  • Key Advantage: Pure β-anomer configuration ensures optimal tyrosinase inhibition and formulation stability

  • Clinical Efficacy:

    • Superior Skin Brightening: 3x more effective than alpha-arbutin in melanin reduction

    • Hyperpigmentation Control: Significantly reduces dark spots and age spots

    • Even Skin Tone: Promotes uniform pigmentation and radiant complexion

  • Recommended Usage: 1-3% in leave-on products, 3-5% in rinse-off formulations

  • Compliance Status: Complies with EU Cosmetics Regulation, FDA guidelines, and ASEAN cosmetic standards

  • Optimal Applications: Serums, creams, lotions, spot treatments, and pharmaceutical depigmenting products

  • Safety Profile: Non-irritating, non-sensitizing, and photostable with excellent consumer tolerance

4. Zhonghong Biotech: Your Technical Partner in Skin Brightening Solutions
Sourcing reliable Beta Arbutin requires a partner with pharmaceutical-grade capabilities. 陕西中宏投资科技有限公司 (Shaanxi Zhonghong Investment Technology Co., Ltd.) combines 28 years of biochemical expertise with state-of-the-art manufacturing to deliver premium active ingredients for global markets.

  • Technical Capabilities:

    • Enzymatic Synthesis: Proprietary biotransformation process ensures highest purity

    • Advanced nga Analytics: HPLC-ELSD, NMR, and mass spectrometry for precise characterization

    • University Collaborations: Joint research with 5 leading institutions for continuous innovation

  • Global Compliance: Full documentation package including COA, MSDS, and regulatory support

5. Scientific Mechanism: Precision Tyrosinase Inhibition
Beta Arbutin’s efficacy stems from its specific molecular interaction with tyrosinase:

  • Competitive inhibition of tyrosine hydroxylase and DOPA oxidase activities

  • Structural similarity to tyrosine enables targeted enzyme binding

  • Glucosidic bond prevents spontaneous hydroquinone release

  • pH-stable performance across formulation matrices (pH 3.5-7.0)

6. Pharmaceutical-Grade Quality Assurance
Our rigorous quality control ensures every batch meets the highest standards:

Certificate of Analysis (COA) Summary – Beta Arbutin (≥99%)

Kategorya Parameter Espesipikasyon Pamaagi sa Pagsulay
Pagkatawo HPLC Retention Time Matches Reference HPLC-ELSD
Kaputli Beta Arbutin ≥ 99.0% HPLC-UV
Alpha Arbutin ≤ 0.5% HPLC-UV
Hydroquinone ≤ 1 ppm HPLC-UV
Kaluwasan Bug-at nga Metal ≤ 10 ppm ICP-MS
Arsenic ≤ 2 ppm ICP-MS
Microbiology Kinatibuk-ang Ihap sa Plate ≤ 100 CFU/g USP <61>
Yeast/Mold ≤ 50 CFU/g USP <61>
Mga pathogen Absent USP <62>

7. Advanced Manufacturing Process
Our cGMP-compliant synthesis ensures superior quality:

  1. Enzyme Selection: Proprietary β-glucosidase optimization

  2. Biotransformation: Controlled enzymatic reaction under optimized conditions

  3. Pagputli: Multi-stage crystallization and chromatography

  4. Crystallization: Precision crystallization for consistent particle size

  5. Pagpauga: Vacuum drying at controlled temperatures

  6. Pagkontrol sa kalidad: Comprehensive analytical testing

8. Professional Applications

  • Mga kosmetiko: Brightening serums, age spot correctors, evening treatments

  • Pharmaceuticals: Melasma and hyperpigmentation treatments

  • Professional Products: Clinical skincare and aesthetic formulations

  • Personal nga Pag-atiman: Whitening toothpaste and body care products

9. Global Supply Chain Excellence

  • Pagputos: 1kg double-bagged with oxygen scavengers, 25kg fiber drums

  • Pagtipig: Cool, dry conditions (15-25°C) in original packaging

  • Kalig-on: 24 months when stored properly

  • Logistics: Global express shipping with full documentation support

10. Technical Partnership Opportunities
Nagtanyag kami:

  • Custom purity grades (97%, 99%, 99.5%)

  • Formulation technical support

  • Regulatory documentation package

  • Stability and compatibility studies

Contact Our Technical Team:

  • Web: www.aiherba.com

  • Email: sales@aiherba.com; liaodaohai@gmail.com

  • Keywords: Beta Arbutin supplier, skin whitening ingredient manufacturer, bulk arbutin, cosmetic active ingredients, pharmaceutical raw materials, cGMP manufacturer, cosmetic ingredient exporter

11. Technical FAQ

  • Q: What’s the difference between alpha and beta arbutin?
    A: Beta arbutin is the natural, more stable form with proven efficacy, while alpha is synthetic and less stable

  • Q: Can you provide hydroquinone-free certification?
    A: Yes, we guarantee ≤1 ppm hydroquinone in all batches

  • Q: What documentation do you provide?
    A: Full COA, MSDS, stability data, and regulatory support documents

  • Q: Do you offer formulation support?
    A: Our technical team provides comprehensive application support

  • Q: What’s your typical lead time for large orders?
    A: 2-3 weeks for standard orders, 4-5 weeks for custom requirements

12. Professional Conclusion
Beta Arbutin remains the gold standard for safe and effective skin brightening in professional formulations. Zhonghong’s pharmaceutical-grade manufacturing and technical expertise ensure consistent quality and performance for demanding cosmetic and pharmaceutical applications.

Contact us today for technical documentation and samples.

Mga pakisayran:

  1. Maeda, K., & Fukuda, M. (1996). Arbutin: mechanism of its depigmenting action in human melanocyte culture. Journal sa Pharmacology ug Experimental Therapeutics

  2. Sugimoto, K., et al. (2005). Synthesis of α-arbutin and its comparison with β-arbutin. Bioscience, Biotechnology, ug Biochemistry

  3. JECFA (2008). Safety evaluation of arbutin. WHO Food Additives Series

  4. SCCS (2015). Opinion on arbutin. Scientific Committee on Consumer Safety

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