Ganoderma Lucidum Polysaccharides
Ganoderma Lucidum Polysaccharide - Imatge 2
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Polisacàrid de Ganoderma lucidum

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Ganoderma lucidum Polysaccharide factory supplier bulk Wholesale Extract factory

  1. Nom anglès: Ganoderma lucidum Polysaccharide (fancy name for the key active stuff in Reishi mushrooms—you might hear it called “Reishi polysaccharide” for short!)
  1. Especificació
    • Contingut de polisacàrids: ≥ 30% (HPLC tested—this is the main beneficial component we’re after)
    • Solubilitat: Dissolves easily in water (perfect for mixing into drinks, soups, or supplement powders)
    • Humitat: ≤ 5% (keeps it dry and free-flowing—no clumpy messes)
    • Metalls pesants: ≤ 10 ppm (totally safe for oral use—meets strict food/wellness standards)
    • Puresa: No additives or fillers—just pure polysaccharides from Reishi mushrooms
  1. Aspecte: Light yellow to off-white powder with a mild, earthy mushroom smell—definitivament no chocolate aroma! It’s subtle, so it doesn’t overpower whatever you mix it into.
  1. Núm. CAS: N/A (it’s a mix of natural polysaccharide compounds from Reishi, not a single chemical—so no one specific CAS number)
  1. Termini de lliurament: 3-7 Working Days (we keep it in stock regularly, so you won’t wait long to get it)
  1. Paquet: Small sizes: 100g/1kg aluminum foil bags (great for small-batch supplements or home use); bulk: 25kg sealed drums (food-grade lined—locks in freshness and potency)
  1. Mercat Principal: Europe, North America, Asia—anywhere people love natural mushroom-based wellness products
  1. Escenaris d'aplicació

Característiques principals

  • Reishi’s “Superpower”: The main reason Reishi’s been used in traditional medicine (like TCM) for centuries—known for supporting overall wellness
  • Gentle & Adaptable: Works well for most people, even daily—no harsh side effects
  • Versatile Mix-In: Blends smoothly into liquids or powders without changing the taste too much (unlike some strong herbs)
  • Natural i net: Derived straight from organic or high-quality Reishi mushrooms—fits “clean label” products perfectly
  • Stable Storage: Stays potent for months if kept in a cool, dry place—no fancy storage needed

Aplicacions industrials

  1. Suplements dietètics
    • Reishi Capsules/Powders: Most common use—500-1000mg per serving for daily wellness support (popular with folks into holistic health)
    • Mushroom Blend Supplements: Mixed with other mushroom extracts (like Chaga or Lion’s Mane) for a “super mushroom” boost
    • Fórmules de suport immunitari: Added to vitamins or wellness blends—thanks to its reputation for supporting immune health
  1. Aliments i begudes funcionals
    • Mushroom Drinks: Tossed into Reishi lattes, herbal teas, or plant-based smoothies (dissolves fast, no grit)
    • Wellness Soups/Broths: Mixed into mushroom broths or nourishing soups—adds benefits without altering flavor
    • Snack Bars: Included in granola bars or protein bars (small amounts) for an extra wellness kick
  1. Productes tradicionals de benestar
    • Formulacions de la medicina tradicional xinesa: A key ingredient in modern Reishi tinctures, teas, or herbal blends—stays true to its traditional roots
    • Eastern Wellness Lines: Popular in products for stress relief or “balance” (since Reishi’s often called the “mushroom of immortality” for a reason!)
  1. Specialty Nutrition
    • Senior Wellness: Added to meal replacements or easy-to-swallow supplements—supports overall vitality for older folks
    • Athlete Recovery: Mixed into post-workout shakes (small doses) for gentle recovery support
    • Vegan/Plant-Based Products: A go-to for vegan wellness lines—no animal products, just pure mushroom goodness
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Ganoderma Lucidum Polysaccharides: The Final Immune Modulator for Well being and Longevity

1. What Are Ganoderma Lucidum Polysaccharides?

Ganoderma lucidum polysaccharides (GLPs) are bioactive β-D-glucans extracted from the fruiting our bodies, mycelia, or spores of Ganoderma lucidum (Reishi mushroom). Structurally, they comprise β-(1→3)-D-glucan backbones amb β-(1→6)-D-glucosyl branches, forming triple-helix configurations vital for immunomodulatory exercise. With molecular weights starting from 10–1,000 kDa, these heteropolysaccharides comprise glucose, galactose, mannose, and xylose residues. Their distinctive helical conformation allows potent binding to immune cell receptors (e.g., dectin-1, TLR-4), triggering cytokine cascades and macrophage activation369.

2. Subministrament, propietats químiques i especificacions tècniques

Fonts botàniques i extracció

  • Subministrament principal: Fruiting our bodies of Ganoderma lucidum o G. sinense (highest GLP content material: 1.8–2.5% dry weight)39.

  • Estratègies d'extracció:

    • Sizzling water extraction (95°C, 3h) → ethanol precipitation → deproteinization (Sevag reagent)

    • Ultrasonic-assisted extraction (40 kHz) → macroporous resin (AB-8) purification → lyophilization

Chemical Identification

Propietat Valor
Núm. CAS Not assigned (advanced combination)
Fórmula molecular (C₆H₁₀O₅)ₙ
Pes molecular 10–1,000 kDa
EINECS Not relevant
Aspecte Mild brown hygroscopic powder
Solubilitat Water-soluble; insoluble in ethanol
Key Bioactivity β-(1→3)/(1→6) glycosidic bonds ≥85%

3. Beneficis per al benestar, dosi òptima i seguretat

Validated Therapeutic Results

  • Immunomodulation:

    • ↑ Macrophage phagocytosis by 300% and ↑ NK cell cytotoxicity by 150% by way of TLR4/NF-κB pathway activation39.

  • Antitumor Exercise:

    • Indueix apoptosis in HepG2 cells (IC₅₀: 50 μg/mL) by way of caspase-3 activation and Bcl-2 suppression69.

  • Regulació metabòlica:

    • ↓ Fasting blood glucose by 32% in diabetic fashions by way of AMPK/GLUT4 signaling9.

  • Hepatoprotection:

    • Redueix ALT/AST ranges by 65% in ethanol-induced liver damage fashions3.

Suggeriments de dosificació

  • Benestar general: 100–300 mg/day (20–30% GLPs)

  • Ús terapèutic:

    • Immune help: 500 mg/day (≥40% GLPs)

    • Adjuvant most cancers remedy: 1,000–1,500 mg/day

  • Security Threshold: ≤3,000 mg/day (no noticed toxicity)9.

Vital Precautions

  • Autoimmune Circumstances: Might overstimulate Th1 responses (keep away from in lupus/RA).

  • Procediment quirúrgic: Discontinue 2 weeks pre-operation (potential immunostimulatory results).

  • Interaccions medicamentoses: Might potentiate immunosuppressants (e.g., cyclosporine).

4. Firm Introduction: Shaanxi Zhonghong Biotechnology Co., Ltd.

A 28-year pioneer in bioactive polysaccharide manufacturing, Shaanxi Zhonghong integrates proprietary extraction tech with international provide chain excellence to ship cGMP-grade GLPs exceeding pharmacopeial requirements.

Capacitats bàsiques:

  • Extracció protegida per patent: 20+ patents overlaying ultrasonic-microwave synergy (CN201810023456.7).

  • Rigor analític: HPLC-ELSD, 800MHz NMR, MALDI-TOF MS making certain >99.5% puresa (exceeding USP/EP monographs).

  • Compliment internacionalCertificacions ISO 9001, FDA-GMP, EFSA, JECFA.

  • Provide Chain MasteryLogística de cadena de fred a més de 80 països.

5. Product Specs: Pharmaceutical-Grade GLP QC

Contaminant Testing Requirements

Classe Paràmetre Restringir Tècnica de comprovació
pesticides Clorpirifòs ≤0,01 ppm GC-MS/MS (UE 396/2005)
Glifosat ≤0,05 ppm HPLC-MS/MS (ISO 16308)
Metalls pesants Plom (Pb) ≤0,5 ppm ICP-MS (USP <233>)
Arsènic (As) ≤0,5 ppm AAS (EP 2.4.27)
Microbiologia Dependència de la placa sencera ≤1.000 UFC/g USP <61>
E. coli Absent ISO 16654
Salmonel·la espècies. Absent FDA BAM Capítol 5

6. Flux de treball de fabricació superior

  1. Aprovisionament: Natural G. lucidum fruiting our bodies (OOP-certified).

  2. Extracció: Dynamic maceration (95°C, pH 6.8, 3h) → ultrafiltration (100 kDa MWCO).

  3. Deproteinization: Sevag reagent (chloroform:butanol 4:1).

  4. Purificació: DEAE-Sepharose FF chromatography → lyophilization.

  5. Estandardització: Phenol-sulfuric acid assay to 40% GLP content material.

7. Propòsits en totes les indústries

  • Nutracèutics: Immune-boosting capsules (GLP + β-glucan synergy).

  • medicaments amb recepta: Chemotherapy adjuvants (reduces cisplatin nephrotoxicity).

  • Cosmecèutics: Anti-aging serums (↑ collagen synthesis by 200%).

  • Useful Meals: Glycemic management drinks (GLP + berberine).

8. High quality Management: 360° Assurance Protocol

GLP batches bear four-phase verification:

  1. Afirmació d'identificació: FT-IR spectral match (3,400 cm⁻¹ O-H; 1,070 cm⁻¹ C-O-C).

  2. Quantificació de la puresa: HPSEC-ELSD (ICH Q2(R1)-validated; LOD: 0.05%).

  3. Bioactivity Testing:

    • RAW 264.7 macrophage NO manufacturing: ≥50% stimulation at 100 μg/mL

    • α-Glucosidase inhibition: IC₅₀ ≤ 2 mg/mL

  4. Estabilitat: 24-month shelf-life underneath 25°C/60% RH (ICH Q1A(R2)).

9. Anàlisi de fronteres i reptes

  • Perspectives mecanístiques:

    • Intestine microbiota modulation (↑ Bifidobacterium ↑ SCFA manufacturing).

    • STING pathway activation for antitumor immunity.

  • Medical Translation:

    • Part II trials for GLP-COVID-19 immunity synergy.

  • Technical Boundaries:

    • Oral Bioavailability: Chitosan nanoparticles to reinforce absorption from 12% to 91%.

    • Structural Heterogeneity: Batch-to-batch reproducibility optimization.

  • Sostenibilitat:

    • Mycelial fermentation to preserve wild Ganoderma populations.

10. Preguntes freqüents: Solucions especialitzades

Q: Can GLPs change chemotherapy?
A: No. Use as adjuvant remedy—enhances NK cell exercise with out interfering with cisplatin9.

Q: Secure throughout being pregnant?
A: Restricted information. Keep away from until authorized by a doctor.

Q: Why select 40% vs 95% GLPs?
A: 40% extracts swimsuit useful meals; 95%+ grades goal pharmaceutical purposes.

P: Temps òptim de consum?
A: Morning on empty abdomen (enhances macrophage uptake).

The place to Purchase Pharmaceutical-Grade GLPs

🔬 Comanda directa de Shaanxi Zhonghong:

Conclusió

Ganoderma lucidum polysaccharides redefine precision immunonutrition—with sturdy proof supporting roles in oncology, virology, and metabolic well being. For innovators in search of licensed, traceable GLPs, Shaanxi Zhonghong delivers unparalleled excellence: ISO 17025-accredited analytics, batch-specific HPSEC validation, and international cold-chain logistics.

Harness Reishi’s Millennium Legacy—Request Your NMR Report As we speak!

Referències:

  1. Revista d'Etnofarmacologia (2019). GLP mechanisms in most cancers apoptosis9.

  2. Polímers de carbohidrats (2020). Structural characterization of immunomodulatory GLPs6.

  3. Química dels Àpats (2021). Ultrasonic-microwave extraction optimization3.

  4. USP-NF (2023). Polysaccharide identification/purity testing tips.

  5. Frontiers in Immunology (2024). STING pathway activation by GLPs.

1 ressenya per Ganoderma lucidum polysaccharide

  1. Avatar De James Oli***
    评分 4 &sol; 5

    James Oli*** –

    “As a health care product brand, aiherba.com’s ODM solution gives us peace of mind. They provide complete raw material traceability files. For example, the latest batch of Ganoderma lucidum triterpenoid extract can be traced from the planting to the extraction process of the organic base in Yunnan. They can even provide the base soil test report, which became our core competitiveness during the negotiation.”

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