Njemačka kamilica
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Njemačka kamilica

German Chamomile supplier bulk factory Wholesale buy Extract factory

  1. Englesko ime: German Chamomile; Matricaria recutita
  1. Specifikacija
    • Sadržaj aktivnih spojeva:
      • Chamazulene ≥ 1.5% (HPLC), α-Bisabolol ≥ 2.0% (HPLC), Apigenin ≥ 1.0% (HPLC)
    • Rastvorljivost: Poorly soluble in water; highly soluble in ethanol (≥ 60 g/100 mL), isopropyl myristate, and other organic solvents
    • Izgled – povezanGubitak sušenjem ≤ 51 TP3T, Teški metali ≤ 10 ppm, Preostali rastvarači ≤ 0,51 TP3T
    • Veličina čestica: Standard powder ≤ 100 μm; micronized powder ≤ 5 μm for better absorption and efficacy
  1. Izgled
    • Light yellow to greenish-yellow fine powder, with a distinct, pleasant floral and herbaceous aroma, not related to chocolate
  1. CAS BR.
    • As a plant extract mixture, no single CAS number; key components: Chamazulene (515-92-4), α-Bisabolol (515-69-5), Apigenin (520-36-5)
  1. Vrijeme isporuke5 – 7 radnih dana
  1. Paket
    • 1 kg/vreća (aluminijska folijska vreća), 25 kg/bačva (dvoslojna PE vreća unutar kartonske bačve)
  1. Glavna pijaca: Global market, especially popular in Europe (Germany, France), North America, and Asia (Japan, South Korea), mainly used in food, pharmaceuticals, cosmetics, and aromatherapy industries
  1. Scenariji primjene

Osnovne nekretnine

  • Aktivne komponente:
    • Hamazulen: A blue-colored sesquiterpene with strong anti-inflammatory, antibacterial, and wound-healing properties. It can reduce skin redness and swelling effectively.
    • α-Bisabolol: A natural sesquiterpene alcohol known for its soothing, antioxidant, and anti-irritant effects. It helps calm sensitive skin and has antibacterial activity against common skin pathogens.
    • Apigenin: A flavonoid with antioxidant, anti-inflammatory, and potential anti-cancer properties. It can protect cells from oxidative damage and regulate inflammatory pathways.
  • Ključne karakteristike
    • Powerful Anti-inflammatory: Inhibits the production of pro-inflammatory cytokines such as TNF-α and IL-6, reducing inflammation in various tissues.
    • Antioksidativna odbrana: Scavenges free radicals like hydroxyl and superoxide anions, protecting cells from oxidative stress and related damage.
    • Antimikrobna aktivnost: Effective against bacteria (e.g., Staphylococcus aureus) and fungi (e.g., Candida albicans), helping prevent infections.
    • Skin Soothing and Healing: Promotes skin repair, reduces itching, and calms irritated skin, making it ideal for sensitive skin care.

Scenariji primjene

1. Hrana i piće

  • Beverage Industry:
    • A primary ingredient in herbal teas, offering a mild, pleasant flavor. It is often blended with other herbs like lemon balm or mint. German chamomile tea is popular for its calming effects and is consumed to relieve stress and aid digestion.
    • Added to fruit juices, functional beverages, and cocktails (0.1 – 0.5% concentration) to enhance flavor and provide potential health benefits, such as reducing digestive discomfort.
  • Confectionery and Dairy:
    • Used in the production of candies, chocolates, and yogurt to impart a unique floral flavor. It also adds antioxidant value, extending the shelf life of these products.

2. Farmaceutski proizvodi

  • Over-the-Counter (OTC) Products:
    • Found in topical creams, ointments, and gels (2 – 5% concentration) for treating minor skin irritations, sunburns, rashes, and eczema. Its anti-inflammatory and soothing properties help relieve symptoms and promote skin healing.
    • Available as oral supplements in capsule or tablet form (300 – 600 mg per serving) to reduce mild anxiety, promote relaxation, and aid sleep. It is also used to alleviate digestive problems like indigestion and gastritis.
  • Biljni lijekovi:
    • A staple in traditional herbal medicine, German chamomile is used to treat a variety of ailments, including colic in infants, menstrual cramps, and mild insomnia. Modern herbal formulations standardize the active ingredient content for consistent efficacy.

3. Kozmetika i lična njega

  • Skin-Care Products:
    • Incorporated into serums, moisturizers, face masks, and toners (1 – 3% concentration) for its hydrating, anti-aging, and anti-inflammatory benefits. It can reduce the appearance of fine lines and wrinkles by protecting the skin from oxidative stress and promoting collagen synthesis.
    • Ideal for sensitive skin products as it calms irritated skin, reduces redness, and strengthens the skin barrier.
  • Njega kose:
    • Added to shampoos, conditioners, and hair treatments to soothe the scalp, reduce dandruff, and promote hair growth. It can also lighten hair naturally over time.

4. Aromatherapy and Wellness

  • Essential Oil and Aromatherapy:
    • German chamomile essential oil, extracted from the flowers, is widely used in aromatherapy. Inhaling its aroma can help reduce stress, anxiety, and promote relaxation. It is often diffused at home, in spas, or used in massage oils.
    • The oil can also be diluted and applied topically for its skin – soothing properties.
  • Bath and Body Products:
    • Added to bath salts, bubble baths, and body washes to create a calming and therapeutic bathing experience. It can help relieve muscle tension and leave the skin feeling soft and refreshed.

5. Zdravlje životinja

  • Pet Care:
    • Used in pet shampoos and topical treatments to relieve itchy, irritated skin in dogs and cats. It can also be given as a supplement to calm anxious pets during travel or stressful situations.
  • Hrana za stoku:
    • Added to poultry and livestock feed (50 – 200 ppm) to improve feed palatability, enhance animal health through its antioxidant and anti-inflammatory effects, and boost overall productivity.

Metode detekcije

  • Visokoefikasna tečna hromatografija (HPLC):
    • Column: C18 (250 × 4.6 mm, 5 μm), Mobile Phase: Acetonitrile – 0.1% formic acid (gradient elution), Flow Rate: 1.0 mL/min, Detection Wavelength: 230 nm (for chamazulene), 280 nm (for α-bisabolol), 360 nm (for apigenin).
  • Gasna hromatografija-masena spektrometrija (GC-MS):
    • Used to analyze volatile components in German chamomile extract, providing detailed information about the chemical profile and helping to identify and quantify key aroma and bioactive compounds.
  • Fourierova transformacijska infracrvena spektroskopija (FTIR):
    • Helps confirm the chemical structure of active compounds by analyzing characteristic absorption peaks, ensuring product quality and authenticity.

Izvor i prednosti

  • Prirodni izvor: German chamomile is native to Europe and Western Asia but is now cultivated globally. It is primarily harvested for its flowers, from which the extract is obtained.
  • Održivi uzgoj: The plant is relatively easy to grow, requiring moderate sunlight and well-drained soil. Modern agricultural practices and sustainable farming methods ensure a consistent supply without significant environmental impact.
  • Svestrane primjene: Its wide range of bioactive properties makes German chamomile extract highly sought after in multiple industries, from health and wellness to beauty and food, driving strong market demand.

Usklađenost s propisima

  • Američka FDA: Regulated as a food additive, dietary supplement ingredient, and is generally recognized as safe (GRAS). Pharmaceutical-grade products must meet Good Manufacturing Practice (GMP) requirements.
  • Uredba EU: Approved as a food flavoring substance and permitted for use in cosmetics under the Cosmetics Regulation (EC) No 1223/2009. Herbal medicinal products containing German chamomile are regulated under traditional herbal medicine directives.
  • Kineski NMPA: Permitted for use in food, pharmaceuticals, and cosmetics, subject to strict quality control and safety standards to ensure product efficacy and consumer safety.
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German Chamomile Extract: Nature’s Soothing Powerhouse & Your Premium Supply

1. What is German Chamomile Extract?

German Chamomile (Matricaria recutita L., synonym Chamomilla recutita) is a revered medicinal herb belonging to the Asteraceae household. Its extract, derived primarily from the colourful blue-flowered capitula (flower heads), is a concentrated supply of bioactive compounds famend for his or her distinctive anti-inflammatory, antispasmodic, wound-healing, and calming properties. This golden-hued liquid or high quality powder represents nature’s potent reply to irritation and stress, utilized for millennia and now validated by fashionable science.

2. Isporuka proizvoda, hemijska svojstva i identifikacija

  • Opskrba: Flower heads of Matricaria recutita L., meticulously harvested at peak bloom.

  • Ključni bioaktivni sastojci:

    • Sesquiterpenes: (-)-α-Bisabolol (Levomenol) and its oxides A, B, & C, Chamazulene (fashioned throughout distillation/extraction).

    • Flavonoids: Apigenin, Apigenin-7-glucoside, Luteolin, Quercetin.

    • Coumarins: Herniarin, Umbelliferone.

    • Unstable Oil: The important oil part is very valued.

  • Vital Identifiers for Key Constituent (α-Bisabolol):

    • Količina u CAS registru: 515-69-5 (Racemic), 23089-26-1 ((-)-α-Bisabolol) – Be aware: German Chamomile extract itself is a fancy combination, however Bisabolol is a serious marker.

    • Molekularni sistem (MF): C15H26O

    • Molekularna težina (MW): 222.37 g/mol

    • EC / EINECS Quantity: 208-205-9 (for (-)-α-Bisabolol)

3. Efficiency, Well being Benefits, Security & Utilization

  • What Defines “Finest”? The “finest” extract prioritizes:

    • Excessive Bioactive Focus: Particularly, elevated ranges of (-)-α-Bisabolol and Apigenin.

    • Čistoća i sigurnost: Rigorous testing to make sure absence of contaminants (heavy metals, pesticides, microbes).

    • Standardizacija: Assured constant ranges of key actives (e.g., 50% Bisabolol, 1.2% Apigenin).

    • Extraction Technique: Supercritical CO2 or light ethanol extraction usually preserves the fragile azulene complicated finest.

  • Highest Content: Extracts standardized particularly for (-)-α-Bisabolol content material (e.g., 50%, 80%) supply the very best focus of this major anti-inflammatory and skin-soothing compound. Apigenin-rich extracts are prized for rest advantages.

  • Koristi i mehanizmi za blagostanje:

    • Potent Anti-inflammatory: Inhibits COX-2, LOX pathways, and pro-inflammatory cytokines (TNF-α, IL-6). Bisabolol and Chamazulene are key mediators. (PMID: 28698405)

    • Pores and skin Soothing & Wound Therapeutic: Accelerates epithelialization, reduces irritation (dermatitis, eczema), combats microbes. Preferrred for topical formulations.

    • Antioksidativna vježba: Scavenges free radicals (ROS), defending cells from oxidative stress.

    • Anxiolytic & Relaxant: Apigenin binds to benzodiazepine receptors within the CNS, selling calmness and sleep high quality.

    • Antispasmodic: Relaxes easy muscle within the GI tract, easing digestive discomfort (cramps, bloating).

    • Antimikrobno sredstvo: Efficient towards sure micro organism and fungi.

  • Each day Consumption & Utilization Tips:

    • Usmeni: Typical dried flower equal: 2-8 grams each day (infusion). For standardized extracts, comply with producer suggestions primarily based on lively focus (e.g., Bisabolol 30-60 mg/day, Apigenin 5-50 mg/day). Seek the advice of a healthcare supplier first.

    • Tematski: Generally used at 0.5-5% in lotions, lotions, serums. Patch take a look at really helpful.

  • Mjere opreza i rezultati na apstraktnoj strani:

    • Typically Acknowledged as Protected (GRAS) for many. Uncommon allergic reactions potential, particularly in Asteraceae-allergic people.

    • Potential interplay with blood thinners (coumarins) and sedatives (Apigenin). Discontinue 2 weeks pre-surgery.

    • Keep away from throughout being pregnant/breastfeeding with out medical recommendation.

    • Photosensitivity potential with very excessive topical doses. Adhere to really helpful concentrations.

4. Premium Supply: Shaanxi Zhonghong Investment Technology Co., Ltd.
Your trusted associate for premium German Chamomile extract is Shaanxi Zhonghong Investment Technology Co., Ltd., a distinguished high-tech enterprise with 28 godina iskustva in bioactive compounds. We combine agile R&D, collaborative innovation, built-in manufacturing, and world distribution, specializing in superior extraction, purification, and utility of plant-derived actives.

  • Osnovno iskustvo: Natural plant extracts, beauty actives, nutraceutical & pharmaceutical elements, pure pigments & sweeteners.

  • Naučna vještina: Strategic alliances with 5 main universities energy our Zajedničke inovacijske laboratorije. Our technological edge is protected by 20+ patenata and includes a globally unique phytochemical compound library.

  • Reducing-Edge QC: Iskorištavanje HPLC, GC-MS, UPLC-QTOF-MS, and Superconducting NMR inside our superior analytical suite, we assure purity requirements exceeding trade norms by 20%+.

  • Svjetski doseg: We provide bespoke ingredient options to multinational pharmaceutical firms, analysis establishments, and premium manufacturers throughout 80+ nacija u Aziji, Evropi i Americi.

  • Nabavka: We import premium uncooked supplies and make use of state-of-the-art, GMP-compliant extraction applied sciences to make sure unparalleled high quality and bioactivity.

5. Product Specs: Rigorous High quality Management
Shaanxi Zhonghong adheres to the strictest high quality protocols. Under is a abstract of our complete testing regime:

Desk: German Chamomile Extract High quality Specs

Klasa parametra Take a look at Merchandise Ograničenje specifikacije Pogledajte Tehniku
Pesticidi Whole DDT ≤ 0,05 mg/kg GC-ECD / GC-MS/MS
Whole BHC ≤ 0,05 mg/kg GC-ECD / GC-MS/MS
Paration ≤ 0,05 mg/kg GC-ECD / GC-MS/MS
Malation ≤ 0,05 mg/kg GC-ECD / GC-MS/MS
Pyrethrins (Whole) ≤ 1,0 mg/kg HPLC-UV / LC-MS/MS
Teški metali Olovo (Pb) ≤ 3,0 mg/kg ICP-MS / AAS
Kadmijum (Cd) ≤ 1,0 mg/kg ICP-MS / AAS
Arsen (As) ≤ 2,0 mg/kg ICP-MS / HG-AAS
Živa (Hg) ≤ 0,1 mg/kg ICP-MS / CV-AAS
Mikrobiologija Whole Cardio Microbial Rely (TAMC) ≤ 10³ CFU/g EP 2.6.12 / USP <61>
Whole Yeast & Mould Rely (TYMC) ≤ 10² CFU/g EP 2.6.12 / USP <61>
Ešerihija koli Odsutan u 1g EP 2.6.13 / USP <62>
Salmonella spp. Odsutan u 10 g EP 2.6.13 / USP <62>
Zlatni stafilokok Odsutan u 1g EP 2.6.13 / USP <62>
Pseudomonas aeruginosa Odsutan u 1g EP 2.6.13 / USP <62>

6. Vrhunski proizvodni kurs
Our German Chamomile extract is produced beneath stringent GMP circumstances:

  1. Nabavka i autentifikacija: Premium flowers sourced, recognized botanically (HPTLC, DNA barcoding).

  2. Priprema: Cautious drying & milling.

  3. Optimized Extraction: Using superior methods (e.g., Supercritical CO2, Low-Temp Ethanol, Hydrodistillation) to maximise bisabolol/chamazulene yield and protect thermolabile compounds.

  4. Pročišćavanje: Multi-stage filtration, centrifugation, and probably chromatographic separation (e.g., Prep-HPLC) for focused enrichment (e.g., excessive Bisabolol).

  5. Fokus: Vacuum evaporation or membrane filtration.

  6. Standardizacija: Exact adjustment to assured lively compound ranges.

  7. Drying (if powder): Spray drying or freeze drying.

  8. Stroga kontrola kvaliteta: Complete analytical testing towards specs (HPLC for actives, ICP-MS for metals, GC-MS/MS for pesticides, Microbiological assays).

7. Various Application Scenarios

  • Kozmetički proizvodi i njega kože: Calming serums, anti-redness lotions, after-sun merchandise, delicate pores and skin formulations, anti-aging serums (combats inflammation-linked getting older), pure child care.

  • Nutraceutici i dijetetski dodaci prehrani: Stress reduction capsules, sleep aids, digestive wellness blends, immune assist formulation (liquid extracts, capsules, tablets).

  • Aromaterapija: Pure German Chamomile important oil (from extract course of).

  • Lijekovi na recept: Topical anti-inflammatory/antiseptic ointments, wound therapeutic preparations, mouthwashes for gingivitis.

  • Njega kose: Soothing shampoos/conditioners for delicate scalp.

8. Beskompromisno upravljanje visokim kvalitetom (QC)
At Shaanxi Zhonghong, QC is paramount. Our built-in strategy spans the whole product lifecycle:

  • Inspekcija ulaznih sirovih materijala: Full id (macroscopic, microscopic, HPTLC, DNA), purity, and efficiency screening.

  • Kontrole u toku (IPC): Vital parameter monitoring (temp, strain, solvent ratios, time) throughout extraction and purification. Intermediate testing ensures course of consistency.

  • Istraživanje stabilnosti: ICH-guided real-time & accelerated stability testing to find out shelf life and optimum storage circumstances.

  • Superior Analytical Suite: Using HPLC-DAD/ELSD/CAD for quantitative evaluation of bisabolol, apigenin, and flavonoids; GC-FID/MS for risky parts; ICP-MS for hint metals; subtle hyphenated methods (UPLC-QTOF-MS) for complete profiling and impurity identification; validated microbiological strategies.

  • Dokumentacija i sljedivost: Full GMP documentation, batch traceability from uncooked materials to completed product.

  • Usklađenost: Adherence to related pharmacopoeias (EP, USP), ISO requirements, and stringent customer-specific necessities. Our 20%+ purity benefit stems from patented purification applied sciences.

9. Sigurno pakovanje i svjetska logistika

  • Pakovanje: Meals-grade HDPE drums with double LDPE liners (liquid), multi-layered foil luggage inside fiber drums (powder). Nitrogen flushing accessible for oxygen-sensitive compounds. Customized packaging options provided.

  • Skladištenje: Cool, dry circumstances (<25°C), shielded from mild. Particular suggestions per Certificates of Evaluation (CoA).

  • Logistika: Environment friendly world transport through air freight, sea freight (FCL/LCL), and categorical couriers. Complete documentation (CoA, MSDS, Certificates of Origin, Phytosanitary). Experience in dealing with customs clearance worldwide.

10. Deep Dive: Well being Mechanisms, Innovation & Analysis

  • Well being Mechanisms Elucidated:

    • (-)-α-Bisabolol: Modulates NF-κB and MAPK signaling pathways, inhibiting pro-inflammatory mediators (NO, PGE2, cytokines). Enhances pores and skin barrier operate through filaggrin upregulation. Demonstrates gastroprotective results. (PMID: 28698405, 24568305)

    • Apigenin: GABA_A receptor partial agonist (anxiolytic), potent antioxidant through Nrf2 activation, COX-2 inhibition, most cancers chemopreventive potential in vitro/vivo.

    • Chamazulene: Potent scavenger of reactive oxygen species (ROS), inhibits leukotriene B4 synthesis. (PMID: 11849834)

  • Industrial Functions & Our Innovation: Past commonplace extracts, Shaanxi Zhonghong pioneers:

    • Poboljšana bioraspoloživost: Improvement of bisabolol/apigenin phospholipid complexes (Phytosomes®) and nanoemulsions.

    • Stabilizacija Primijenjene nauke: Encapsulation to guard chamazulene from degradation.

    • Inexperienced Extraction: Optimization of UAE (Ultrasound-Assisted Extraction) and MAE (Microwave-Assisted Extraction) for effectivity and sustainability.

    • Sinergijske mješavine: Formulating with complementary actives (e.g., Centella Asiatica, Licorice) for amplified results.

  • Granice i izazovi analize:

    • Medicinski prijevod: Bigger, strong human scientific trials confirming mechanistic advantages, particularly for inner use (anxiousness, GI well being).

    • Novel Supply Techniques: Exploring transdermal patches, nanoparticle carriers for focused supply.

    • Složenost standardizacije: Defining multi-marker standardization reflecting holistic exercise vs. single compounds.

    • Održivi uzgoj: Making certain moral sourcing, biodiversity conservation, and mitigating local weather change impression on chamomile high quality/yield.

    • Metabolomics & Synergy: Superior methods (metabolomics) to completely map constituents and perceive their complicated synergistic interactions (“entourage impact”).

11. Često postavljana pitanja (FAQ)

  • Q: What is the distinction between German and Roman Chamomile? A: Completely different species (Chamaemelum nobile). German Chamomile sometimes comprises greater ranges of chamazulene and bisabolol, providing stronger anti-inflammatory motion. Roman Chamomile oil is greater in esters, recognized for deeper nervous system calming.

  • Q: Is your German Chamomile extract standardized? To what? A: Sure. We provide numerous standardizations, primarily focusing on excessive ranges of (-)-α-Bisabolol (e.g., 50%, 80%) or Apigenin (e.g., 1.2%, 4%). Customized standardization is on the market.

  • P: Koje certifikate održavate? A: We function beneath strict GMP, ISO 9001, ISO 22000, and maintain Kosher, Halal, and Natural (the place relevant) certifications. Particular certifications per product accessible on request.

  • P: Koji je rok trajanja? A: Sometimes 24 months from manufacturing date when saved appropriately (cool, dry, darkish). Confer with the particular CoA.

  • Q: What is the Minimal Order Amount (MOQ)? A: MOQ varies relying on the particular extract and packaging. Please contact us for particulars.

  • Q: Do you supply pattern testing? A: Sure, we offer samples for certified patrons and potential companions.

  • Q: Is it protected for topical use on delicate pores and skin? A: Extremely regarded for delicate pores and skin. All the time patch take a look at first and use inside really helpful concentrations (sometimes 0.5-5%).

  • Q: Can it’s taken orally each day? A: Sure, inside really helpful dosages primarily based on the extract power. Seek the advice of a healthcare skilled for personalised recommendation, particularly if pregnant, nursing, taking drugs, or have well being circumstances.

12. The place to Purchase Premium German Chamomile Extract
Accomplice with the chief in bioactive plant compounds. Supply your high-purity, scientifically-backed German Chamomile extract straight from the producer:

  • Kontakt: g. Liao Daohai

  • E-pošta: liaodaohai@gmail.com

  • Web stranica: www.aiherba.com

  • Inquire About: Bulk pricing, customized standardizations (Bisabolol, Apigenin), samples, certifications (ISO, Kosher, Halal), and technical knowledge sheets (TDS).

13. Zaključak
German Chamomile extract, significantly wealthy in (-)-α-Bisabolol and Apigenin, stands as a scientifically validated, multi-functional botanical powerhouse. Its profound anti-inflammatory, soothing, and calming properties make it indispensable in premium skincare, nutraceuticals, and wellness merchandise. Shaanxi Zhonghong Investment Technology Co., Ltd. leverages 28 years of experience, cutting-edge extraction expertise (HPLC, NMR), patented purification processes, and unwavering dedication to high quality (exceeding purity requirements by 20%+) to ship the world’s best German Chamomile extracts. Backed by rigorous QC, world logistics, and a dedication to innovation, we empower manufacturers to harness nature’s potent blue flower for superior product efficacy and shopper belief. Contact us immediately to raise your formulations.

14. References (Illustrative)

  1. European Pharmacopoeia (Ph. Eur.) eleventh Version – Matricaria Flower / Matricariae Flos.

  2. Blumenthal, M., et al. (Eds.). (2000). The Full German Fee E Monographs. American Botanical Council. (Chamomile Monograph).

  3. Srivastava, J. Okay., Shankar, E., & Gupta, S. (2010). Chamomile: A natural drugs of the previous with vibrant future. Molecular Medication Stories, 3(6), 895–901. PMID: 21132119

  4. Amsterdam, J. D., et al. (2009). A randomized, double-blind, placebo-controlled trial of oral Matricaria recutita (chamomile) extract remedy for generalized anxiousness dysfunction. Journal of Medical Psychopharmacology, 29(4), 378–382. PMID: 19593179

  5. McKay, D. L., & Blumberg, J. B. (2006). A evaluate of the bioactivity and potential well being advantages of chamomile tea (Matricaria recutita L.). Analiza fitoterapije, 20(7), 519–530. PMID: 16628544

  6. Worldwide Journal of Beauty Science, numerous articles on chamomile pores and skin efficacy.

  7. Shaanxi Zhonghong Inner Analysis & Patents

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