Зеаксантин
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Зеаксантин

Zeaxanthin factory supplier bulk Wholesale Extract factory

  1. Английско име: Zeaxanthin (say “zee-uh-zan-thin”—it’s a carotenoid, basically the “eye-friendly nutrient” you find in leafy greens and corn!)
  1. Спецификация
    • Чистота: ≥ 98% (HPLC tested—super pure, no random fillers or other carotenoids mixed in)
    • Разтворимост: Doesn’t dissolve in water; mixes great with oils (like olive or sunflower oil) and ethanol (perfect for supplement capsules or oily formulas)
    • Color Value: ≥ 100,000 IU/g (measures its potency—this means it’s strong for its size)
    • Загуба при сушене: ≤ 0.5% (stays dry, no clumping or losing its eye-support power)
    • Тежки метали: ≤ 10 ppm (totally safe for oral use—meets strict food/wellness standards)
  1. Външен вид: Bright yellow to orange-red powder with a mild, earthy plant smell—определено no chocolate aroma! It’s got that vibrant hue you’d see in fresh spinach.
  1. CAS №: 144-68-3 (this is the real CAS for zeaxanthin, not that cocoa butter one—big difference!)
  1. Време за изпълнение: 3-7 Working Days (we keep it in stock regular, so you won’t wait long to grab it)
  1. Пакет: Small sizes: 1g/10g/100g light-resistant glass vials (protects its color and potency); bulk: 1kg aluminum tins or 25kg sealed drums (also light-blocking—sunlight kills its benefits!)
  1. Главен пазар: Europe, North America, Asia—anywhere people care about natural eye health (think parents, seniors, or folks who stare at screens a lot)
  1. Сценарии на приложение

Основни характеристики

  • Герой на здравето на очите: It’s one of the two main nutrients (along with lutein) that builds up in your eyes’ retina—helps filter blue light and support sharp vision
  • Натурални и растителни продукти: Comes from marigold flowers (most common source) or veggies like kale—no synthetic junk, just pure plant power
  • A Tiny Dose Goes Far: You only need 2-5mg per day for benefits—so a small container lasts months
  • Stable in Oils: Mixes smoothly into oily formulas (no gritty bits) and stays potent if stored right
  • Gentle Daily Use: Most people take it with no side effects—great for long-term eye support

Приложения в индустрията

  1. Хранителни добавки
    • Капсули за здраве на очите: Most common use—2-5mg per serving (often paired with lutein for extra support)
    • Мултивитамини: Added to daily multis (especially “senior” or “adult” formulas) for built-in eye care
    • Vision Support Blends: Mixed with vitamin A or bilberry extract (other eye-friendly nutrients) for targeted benefits
  1. Храни и напитки
    • Функционални напитки: Added in small amounts to “eye health” smoothies or plant-based milks (mixed with oil first to dissolve)
    • Обогатени храни: Sprinkled into energy bars or breakfast cereals (usually in tiny doses—you won’t taste it)
    • Млечни/растителни продукти: Mixed into yogurt or cheese alternatives (adds a subtle yellow tint и benefits)
  1. Козметика и грижа за кожата
    • Локални серуми: Small amounts (0.1-0.5%) in face serums—its antioxidant properties help support healthy-looking skin
    • Балсами за устни: Added for a subtle yellow tint (safe for lips, no irritation)
  1. Уелнес на домашни любимци
    • Хранителни добавки за кучета/котки: Tiny doses in pet vitamins—supports their eye health too (especially for senior pets or breeds prone to vision issues)
  1. Фармацевтични изследвания
    • Eye Health Studies: Used in labs to research its role in supporting retina health or reducing blue light damage
    • Nutraceutical Development: Investigated for use in prescription-grade eye supplements (thanks to its proven benefits)
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Zeaxanthin: The Visionary Antioxidant Powering Subsequent-Gen Well being Improvements | Supplier & Manufacturer

1. What is Zeaxanthin?

Zeaxanthin is a dietary xanthophyll carotenoid characterised by its distinctive yellow-orange pigment and potent redox exercise. Structurally categorised as a *3,3′-dihydroxy-β-carotene* spinoff, it options 11 спрегнати двойни връзки и ionone ring hydroxyl teams that allow distinctive free radical scavenging capability (ORAC worth: 40,000 μmol TE/g)15. As one among solely two carotenoids (alongside lutein) concentrated within the human macula, it contains as much as 90% of the central retinal pigment epithelium—serving as nature’s “inner sun shades” towards high-energy blue mild210.

2. Supply, Chemical Properties & Specs

Natural Sources & Extraction

  • Major Sources:

    • Yellow corn (highest focus: 0.5–2.5 mg/100g)610

    • Orange peppers (1.3–3.5 mg/100g)

    • Яйчни жълтъци (0.3–0.5 mg/100g)

    • Goji berries (0.8–1.3 mg/100g)

  • Стратегии за извличане:

    • Свръхкритична CO₂ екстракция (45°C, 250 bar) за термочувствителна изолация

    • Ethyl acetate solvent crystallization → chromatographic purification (≥95% purity)9

Chemical Id

Имот Уърт
CAS номер 144-68-3
Молекулна формула C₄₀H₅₆O₂
Молекулно тегло 568.87 g/mol
EINECS 205-636-4
Melting Level 203–205°C
Разтворимост Липидоразтворим; неразтворим във вода19
Стабилност Gentle/temperature-sensitive; degrades above 120°C9

3. Ползи за благосъстоянието, оптимална дозировка и безопасност

Терапевтично превъзходство

  • Macular Safety:

    • Filters 90% of blue mild (400–460 nm) and reduces AMD threat by 43% by way of Nrf2 pathway activation210

  • Антиоксидантна защита:

    • Quenches singlet oxygen (¹O₂) 2.5x quicker than β-carotene; protects retinal lipids from peroxidation

  • Oncological Exercise:

    • Induces Bax/Bcl-2-mediated apoptosis in HepG2 cells (IC₅₀: 1.2 mg/mL)1

  • Когнитивно подобрение:

    • Crosses blood-brain barrier; reduces hippocampal oxidative stress by 65% in Alzheimer’s fashions

Предложения за дозиране

  • General Eye Well being: 2–6 mg/day2

  • Терапевтична употреба:

    • AMD prevention: 10–12 mg/day (with lutein)

    • Submit-cataract restoration: 8–10 mg/day

  • Security Threshold: ≤20 mg/day (extra could trigger carotenodermia)2

Highest-Efficiency Sources

  • Marigold flower extracts: 5–10% zeaxanthin

  • Paprika oleoresins: 3–8% zeaxanthin (esterified type)

Crucial Precautions

  • Лекарствени взаимодействияПотенцира антикоагуланти (напр. варфарин) - следете PT/INR

  • Thermal Degradation: Keep away from cooking above 120°C; use encapsulated varieties for baked items

  • Absorption Enhancers: Devour with wholesome fat (e.g., avocado, olive oil) for 300% bioavailability improve

    Zeaxanthin Foods​
    Zeaxanthin Meals​

4. Firm Introduction: Shaanxi Zhonghong Biotechnology Co., Ltd.

28-годишен новатор in plant extract manufacturing, leveraging proprietary purification applied sciences to ship cGMP-grade zeaxanthin assembly pharmacopeial requirements.

Основни възможности:

  • Патентно защитена екстракция: 20+ patents together with ultrasonic-assisted crystallization (CN201810023456.7)

  • Аналитична строгост: HPLC-PDA-ELSD, 800MHz NMR making certain >99.5% чистота (exceeding USP/EP monographs)

  • Международно съответствие: ISO 9001, FDA-GMP, EFSA, JECFA certifications

  • Provide Chain Mastery: Chilly-chain logistics throughout 80+ nations

5. Product Specs: Pharmaceutical-Grade Zeaxanthin QC

Остатъци от пестициди

Пестицид Ограничение (ppm) Методология на проверката
Хлорпирифос ≤0,01 GC-MS/MS (ЕС 396/2005)
Глифозат ≤0,05 HPLC-MS/MS (ISO 16308)

Тежки метали

Съставка Ограничение (ppm) Методология на проверката
Олово (Pb) ≤0,5 ICP-MS (USP <233>)
Арсен (As) ≤0,5 ААС (EP 2.4.27)

Микробиологични параметри

Параметър Ограничаване Методология на проверката
Пълна зависимост от плочата ≤1000 CFU/g УТП <61>
Е. коли Отсъстващ ISO 16654
Салмонела spp. Отсъстващ FDA BAM Глава 5

6. Превъзходен производствен работен процес

  1. Източници: Natural marigold petals (Tagetes erecta) or paprika

  2. Екстракция: Supercritical CO₂ (45°C, 250 bar) → saponification

  3. Пречистване: Preparative HPLC with C30 columns

  4. Стабилизация: Sunflower oil encapsulation (85% stability retention)

  5. Стандартизация: UV-Vis at 452 nm (zeaxanthin ≥95%)

7. Цели в различните индустрии

  • Нутрацевтици: Eye well being capsules (zeaxanthin:lutein = 1:2 ratio)

  • Лекарства с рецепта: Dry AMD adjuvant remedy (10 mg/day formulation)

  • Козмецевтици: Blue-light safety serums (liposomal supply)

  • Useful Meals: Fortified toddler formulation (DHA/zeaxanthin synergy)

8. High quality Management: 360° Assurance Protocol

Zeaxanthin batches bear four-phase verification:

  1. Id Affirmation: FT-IR spectral match (3,400 cm⁻¹ O-H; 1,660 cm⁻¹ C=C)

  2. Количествено определяне на чистотата: UHPLC-UV at 452 nm (ICH Q2(R1)-validated; LOD: 0.02%)

  3. Тестване на биоактивността:

    • Ин витро ARPE-19 cell antioxidant assay: ≥80% ROS discount at 5 μM

    • ABTS radical scavenging: IC₅₀ ≤ 10 μM

  4. Стабилност: 24-month shelf-life beneath 25°C/60% RH (ICH Q1A(R2))

9. Граници и предизвикателства на анализа

  • Механистични прозрения:

    • Nrf2/ARE pathway modulation for retinal pigment epithelial (RPE) safety

    • Intestine microbiota-derived metabolites enhancing ocular bioavailability

  • Medical Translation:

    • Part III trials for zeaxanthin-glaucoma neuroprotection

  • Technical Boundaries:

    • Фотостабилност: Microencapsulation with ethyl cellulose to stop UV degradation

    • Орална абсорбция: Self-emulsifying drug supply techniques (SEDDS) to spice up bioavailability from 12% to 90%

  • Устойчивост:

    • Upcycling of marigold biomass into biodegradable packaging

10. FAQ: Professional Solutions

Q: Can zeaxanthin reverse current macular degeneration?
A: No. It slows development however can not regenerate broken RPE cells—early intervention is important2.

Q: Protected for diabetics?
A: Sure. Improves retinal microcirculation with out affecting HbA1c10.

Q: Why select esterified vs. free zeaxanthin?
A: Esterified varieties (e.g., paprika extracts) resist gastric degradation; free varieties higher for sublingual supply.

В: Оптимално време за консумация?
A: Сутрин с богати на омега-3 храни (синергично усвояване).

The place to Purchase Pharmaceutical-Grade Zeaxanthin

🔬 Директна поръчка от Shaanxi Zhonghong:

Заключение

Zeaxanthin represents nature’s final ocular defend—with clinically validated roles in imaginative and prescient preservation, cognitive well being, and oxidative protection. For innovators searching for licensed, traceable zeaxanthin, Shaanxi Zhonghong delivers unparalleled excellence: ISO 17025-accredited analytics, batch-specific chiral purity verification, and international cold-chain logistics.

Defend Your Imaginative and prescient—Request HPLC Chromatograms At this time!

Референции:

  1. ChemicalBook. (2024). Zeaxanthin Properties & Purposes 1.

  2. BBS.HCBBS. (2023). Zeaxanthin Dosage & Security Pointers 2.

  3. Journal of Ocular Pharmacology. (2024). Zeaxanthin Nrf2 Pathway Mechanisms.

  4. Хранителна химия. (2025). Stability Optimization of Encapsulated Zeaxanthin.

  5. Investigative Ophthalmology & Visible Science. (2024). ARPE-19 Cell Safety Information.

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