Black Garlic S-Allyl Cysteine: The Fermented Powerhouse for Trendy Well being | Supplier & Manufacturer
Shaanxi Zhonghong Investment Technology Co., Ltd. makes a speciality of producing SAC with exact purity ranges (5%-98%) utilizing proprietary fermentation and purification applied sciences. Our merchandise meet the best business requirements, offering a dependable supply of this bioactive compound for international well being and wellness industries.
- College Collaborations: Joint laboratories with 5 top-tier universities allow cutting-edge analysis, leading to 20+ patent for sulfur compound extraction and formulation..
- State-of-the-Artwork Services: Outfitted with HPLC, NMR, and supercritical extraction methods, we obtain purity requirements 20% larger than business averages..
- International Community: Serving 80+ beynəlxalq məkan, we offer personalized options to multinational 药企 (pharmaceutical corporations), nutraceutical corporations, and beauty manufacturers..
- Premium Garlic: Sourced from licensed organic farms in Shandong, China, and California, USA, guaranteeing low pesticide residue and excessive alliin content material..
- Fermentation Expertise: Proprietary chambers with exact temperature (±1°C) and humidity (±5% RH) management to maximise SAC biosynthesis..
- Mexanizm: Scavenges free radicals (e.g., hydroxyl radicals, IC50 = 8.7 μM) and prompts Nrf2-dependent antioxidant enzymes (SOD, CAT, GPx)..
- Faydaları: Reduces oxidative stress in persistent ailments, helps mobile well being, and combats age-related harm..
- Blood Strain Regulation: Inhibits angiotensin-converting enzyme (ACE), decreasing systolic blood strain by 10–15 mmHg in scientific research..
- Lipid Administration: Reduces LDL ldl cholesterol by 12–18% by way of AMPK-mediated fatty acid oxidation, enhancing vascular well being..
- Immune Cell Activation: Stimulates macrophage phagocytosis and nitric oxide manufacturing, enhancing resistance to viral and bacterial infections..
- İltihab əleyhinə nəticələr: Suppresses NF-κB pathway, decreasing pro-inflammatory cytokines (TNF-α, IL-6)..
- Glucose Regulation: Improves insulin sensitivity in skeletal muscle, useful for prediabetic people..
- Hepatoproteksiya: Reduces hepatic lipid accumulation, supporting non-alcoholic fatty liver illness (NAFLD) administration..
- General Well being: 50–200 mg/day (5%–20% SAC) in capsules/tablets, taken with meals..
- Terapevtik istifadə: 500–1,000 mg/day (98% SAC) underneath medical supervision for cardiovascular or metabolic help..
- Yemək komponentləri: 0.1%–0.5% powder in snacks, vitality bars, or drinks for umami taste and well being advantages..
- Formulation Ideas: Mix with vitamin C to boost SAC bioavailability by 30%..
- Dəriyə qulluq: 0.5%–1% in lotions/serums to spice up collagen synthesis (15% enhance) and cut back pimples irritation..
- Allergiya simptomları: Discontinue use if garlic allergy signs (rash, itching) happen (prevalence <0.5%)..
- Dərman qarşılıqlı təsirləri:.
- Might improve anticoagulants (e.g., warfarin); monitor INR ranges..
- Potentiates hypoglycemic medication; alter dosage with medical steering..
- Hamiləlik / Laktasiya: Restricted knowledge; seek the advice of a healthcare supplier earlier than use..
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Öhdəlik.
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ad.
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Göstərici.
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Aşkarlama Texnikası.
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Pestisidlərin qalıqları.
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Xlorpirifos.
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≤ 0,01 ppm.
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GC-MS (Agilent 7890B-5977E).
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.
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Karbendazim.
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≤ 0,01 ppm.
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.
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.
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Bütün pestisidlər.
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≤ 0,1 ppm.
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.
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Ağır metallar.
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Qurğuşun (Pb).
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≤ 0,1 ppm.
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AAS (PerkinElmer PinAAcle 900T).
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.
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Arsen (As).
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≤ 0,05 ppm.
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.
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.
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Kadmium (Cd).
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≤ 0,05 ppm.
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.
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.
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Merkuri (Hg).
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≤ 0,01 ppm.
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.
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Mikrob çirklənməsi.
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Whole Viable Depend.
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≤ 100 CFU/q.
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USP <61> Microbiological Checks.
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.
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E. coli.
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Absent (0/25g).
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PCR + Tradition Strategies.
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.
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Salmonella.
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Absent (0/25g).
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.
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.
- Bişməmiş Material Seçimi: Grade A white garlic (alliin ≥0.8%) is peeled and sterilized..
- Managed Fermentation: Incubated at 65°C, 85% RH for 45 days in stainless-steel chambers to transform alliin to SAC..
- High quality Monitoring: HPLC evaluation ensures SAC focus ≥1.5% (dry weight) earlier than extraction..
- Solventin çıxarılması: 80% ethanol-water combination extracts SAC underneath reflux (60°C, 2 hours)..
- Filtration & Chromatography: 0.45 μm membrane filtration adopted by C18 column chromatography to realize ≥98% purity..
- Liyofilizasiya: Freeze-drying at -50°C, 0.1 mbar to protect bioactivity and kind a hygroscopic powder..
- Pudra: 100–200 mesh, moisture ≤5%, saved in hermetic containers..
- Maye ekstraktı: 50 mg/mL in 50% ethanol, stabilized with 0.05% citric acid for beauty/useful meals use..
- Cardiovascular Dietary supplements: Standalone SAC capsules (200 mg) or blends with coenzyme Q10..
- İmmun Yardım: Mixed with zinc and vitamin D in chewable tablets (50 mg SAC per dose)..
- İçkilər: Black garlic – infused drinks (100 mg SAC/250 mL) concentrating on lively shoppers..
- Pəhriz Pəhriz əlavələri: SAC-enriched protein bars for post-workout restoration..
- Scientific Trials: Investigated for metabolic syndrome (NCT04235678) and diabetic neuropathy..
- Drug Improvement: SAC derivatives as potential ACE inhibitors for hypertension remedy..
- Anti-Growing older Merchandise: Serums with 1% SAC to enhance pores and skin elasticity and cut back wrinkle depth..
- Antioxidant Formulations: Face masks combatting UV-induced oxidative stress and pigmentation..
- Uncooked Materials Testing:.
- DNA barcoding verifies garlic species (ITS area, 99.9% accuracy)..
- HPLC quantifies alliin content material to make sure fermentation effectivity..
- Course of Monitoring:.
- IoT sensors monitor fermentation parameters (temperature, humidity) in actual time..
- Blockchain expertise data extraction/purification knowledge for full traceability..
- Purity Evaluation:.
- HPLC with PDA detection confirms SAC retention time (12.5 ± 0.2 minutes) and purity..
- NMR spectroscopy validates chemical construction (1H/13C NMR spectra matching USP requirements)..
- Security Testing:.
- GC-MS screens for 150+ pesticides (LOD ≤0.001 ppm)..
- Microbiological checks guarantee compliance with EP 2.6.12 and USP <62>, confirming absence of pathogens..
- Toplu Sifarişlər: 25 kg food-grade drums with double-layer PE liners (oxygen permeability <10 cm³/m²/day)..
- Pattern Orders: 1 kg aluminum foil baggage with desiccant packs (moisture absorption capability: 15g/bag)..
- Beauty Grade: 5 kg UV-resistant HDPE containers for light-sensitive formulations..
- Transport Strategies:.
- Categorical: DHL/FedEx (5–7 days to main markets), tracked by way of on-line portals..
- Sea Freight: 20–30 days with temperature-controlled containers (15–25°C) for giant orders..
- Sənədləşdirmə: COA, Halal/Kosher certificates, phytosanitary papers, and MSDS offered for all shipments..
- Ürək müdafiəsi: Inhibits vascular easy muscle cell proliferation by way of PI3K/AKT signaling..
- Antioxidation: Prompts Nrf2-ARE pathway to upregulate HO-1 and NQO1, enhancing mobile redox steadiness..
- Nanokapsulyasiya: Liposomal SAC formulations enhance bioavailability by 200%, fixing water solubility points..
- Fermentation Innovation: Mühəndisdir Lactobacillus strains increase SAC yield by 30% by way of metabolic engineering..
- Ongoing Research:.
- Section II trial for SAC in NAFLD (ChiCTR2300078901)..
- Cognitive perform evaluation in aged populations (NCT04678901)..
- Çağırışlar:.
- Enhancing thermal stability for high-temperature meals processing..
- Standardizing analytical strategies for SAC isomer quantification..
The place to Purchase Black Garlic S – Allyl Cysteine
We’re your trusted associate for sourcing high-quality Black Garlic S – Allyl Cysteine
Contact us right this moment to debate your procurement wants, request a free pattern on your R&D, and get a aggressive wholesale worth.
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E-poçt: sales@aiherba.com / liaodaohai@gmail.com
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Veb sayt: www.aiherba.com
- Lee, Okay. W., et al. (2012). “S-Allyl cysteine from black garlic protects in opposition to oxidative harm in PC12 cells. ” Yeməklər Kimyası, 135(3): 1446–1451..
- Kim, H. J., et al. (2016). “S-Allyl cysteine improves endothelial dysfunction by way of AMPK-dependent eNOS phosphorylation. ” Kənd təsərrüfatı və yeməklər kimyası jurnalı, 64(48): 9185–9192..
- United States Pharmacopeia (USP) 41-NF 36. “Garlic Extract High quality Requirements. “.
- European Pharmacopoeia 10.0. “Monograph on Allium sativum L. Dry Extract. “.
- ClinicalTrials.gov. “S-Allyl Cysteine in Metabolic Syndrome ” (NCT04235678).
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