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Ganoderma lucidum polisaxarid

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Ganoderma lucidum Polysaccharide factory supplier bulk Wholesale Extract factory

  1. İngilis adı: Ganoderma lucidum Polysaccharide (fancy name for the key active stuff in Reishi mushrooms—you might hear it called “Reishi polysaccharide” for short!)
  1. Spesifikasiya
    • Polisaxarid tərkibi: ≥ 30% (HPLC tested—this is the main beneficial component we’re after)
    • Həlledicilik: Dissolves easily in water (perfect for mixing into drinks, soups, or supplement powders)
    • Nəmlik: ≤ 5% (keeps it dry and free-flowing—no clumpy messes)
    • Ağır metallar: ≤ 10 ppm (totally safe for oral use—meets strict food/wellness standards)
    • Saflıq: No additives or fillers—just pure polysaccharides from Reishi mushrooms
  1. Görünüş: Light yellow to off-white powder with a mild, earthy mushroom smell—mütləq no chocolate aroma! It’s subtle, so it doesn’t overpower whatever you mix it into.
  1. CAS NO.: N/A (it’s a mix of natural polysaccharide compounds from Reishi, not a single chemical—so no one specific CAS number)
  1. Təqdimat vaxtı: 3-7 Working Days (we keep it in stock regularly, so you won’t wait long to get it)
  1. Paket: Small sizes: 100g/1kg aluminum foil bags (great for small-batch supplements or home use); bulk: 25kg sealed drums (food-grade lined—locks in freshness and potency)
  1. Əsas bazar: Europe, North America, Asia—anywhere people love natural mushroom-based wellness products
  1. Tətbiq Ssenariləri

Əsas Xüsusiyyətlər

  • Reishi’s “Superpower”: The main reason Reishi’s been used in traditional medicine (like TCM) for centuries—known for supporting overall wellness
  • Gentle & Adaptable: Works well for most people, even daily—no harsh side effects
  • Çox yönlü Mix-In: Blends smoothly into liquids or powders without changing the taste too much (unlike some strong herbs)
  • Təbii və Təmiz: Derived straight from organic or high-quality Reishi mushrooms—fits “clean label” products perfectly
  • Stable Storage: Stays potent for months if kept in a cool, dry place—no fancy storage needed

Sənaye Tətbiqləri

  1. Pəhriz əlavələri
    • Reishi Capsules/Powders: Most common use—500-1000mg per serving for daily wellness support (popular with folks into holistic health)
    • Mushroom Blend Supplements: Mixed with other mushroom extracts (like Chaga or Lion’s Mane) for a “super mushroom” boost
    • İmmunitet Dəstəyi Formulaları: Added to vitamins or wellness blends—thanks to its reputation for supporting immune health
  1. Funksional Qidalar və İçkilər
    • Mushroom Drinks: Tossed into Reishi lattes, herbal teas, or plant-based smoothies (dissolves fast, no grit)
    • Wellness Soups/Broths: Mixed into mushroom broths or nourishing soups—adds benefits without altering flavor
    • Snack Bars: Included in granola bars or protein bars (small amounts) for an extra wellness kick
  1. Ənənəvi Sağlamlıq Məhsulları
    • TCM Formulations: A key ingredient in modern Reishi tinctures, teas, or herbal blends—stays true to its traditional roots
    • Eastern Wellness Lines: Popular in products for stress relief or “balance” (since Reishi’s often called the “mushroom of immortality” for a reason!)
  1. Specialty Nutrition
    • Senior Wellness: Added to meal replacements or easy-to-swallow supplements—supports overall vitality for older folks
    • Athlete Recovery: Mixed into post-workout shakes (small doses) for gentle recovery support
    • Vegan/Plant-Based Products: A go-to for vegan wellness lines—no animal products, just pure mushroom goodness

Ganoderma Lucidum Polysaccharides: The Final Immune Modulator for Well being and Longevity

1. What Are Ganoderma Lucidum Polysaccharides?

Ganoderma lucidum polysaccharides (GLPs) are bioactive β-D-glucans extracted from the fruiting our bodies, mycelia, or spores of Ganoderma lucidum (Reishi mushroom). Structurally, they comprise β-(1→3)-D-glucan backbones ilə β-(1→6)-D-glucosyl branches, forming triple-helix configurations vital for immunomodulatory exercise. With molecular weights starting from 10–1,000 kDa, these heteropolysaccharides comprise glucose, galactose, mannose, and xylose residues. Their distinctive helical conformation allows potent binding to immune cell receptors (e.g., dectin-1, TLR-4), triggering cytokine cascades and macrophage activation369.


2. Təchizat, Kimyəvi Xüsusiyyətlər və Texniki Xüsusiyyətlər

Botanika Mənbələri və Ekstraksiya

  • Əsas Təchizat: Fruiting our bodies of Ganoderma lucidum və ya G. sinense (highest GLP content material: 1.8–2.5% dry weight)39.

  • Çıxarma strategiyaları:

    • Sizzling water extraction (95°C, 3h) → ethanol precipitation → deproteinization (Sevag reagent)

    • Ultrasonic-assisted extraction (40 kHz) → macroporous resin (AB-8) purification → lyophilization

Chemical Identification

Əmlak dəyər
CAS nömrəsi Not assigned (advanced combination)
Molekulyar Formula (C₆H₁₀O₅)ₙ
Molekulyar Çəki 10–1,000 kDa
EINECS Not relevant
Görünüş Mild brown hygroscopic powder
Həlledicilik Water-soluble; insoluble in ethanol
Key Bioactivity β-(1→3)/(1→6) glycosidic bonds ≥85%

3. Sağlamlığın Faydaları, Optimal Dozaj və Təhlükəsizlik

Təsdiqlənmiş Terapevtik Nəticələr

  • İmmunomodulyasiya:

    • ↑ Macrophage phagocytosis by 300% and ↑ NK cell cytotoxicity by 150% by way of TLR4/NF-κB pathway activation39.

  • Antitumor Exercise:

    • İnduksiya edir apoptosis in HepG2 cells (IC₅₀: 50 μg/mL) by way of caspase-3 activation and Bcl-2 suppression69.

  • Metabolik tənzimləmə:

    • ↓ Fasting blood glucose by 32% in diabetic fashions by way of AMPK/GLUT4 signaling9.

  • Hepatoproteksiya:

    • azaldır ALT/AST ranges by 65% in ethanol-induced liver damage fashions3.

Dozajla bağlı təkliflər

  • Ümumi Sağlamlıq: 100–300 mg/day (20–30% GLPs)

  • Terapevtik istifadə:

    • Immune help: 500 mg/day (≥40% GLPs)

    • Adjuvant most cancers remedy: 1,000–1,500 mg/day

  • Təhlükəsizlik həddi: ≤3,000 mg/day (no noticed toxicity)9.

Vital Precautions

  • Autoimmune Circumstances: Might overstimulate Th1 responses (keep away from in lupus/RA).

  • Cərrahi prosedur: Discontinue 2 weeks pre-operation (potential immunostimulatory results).

  • Dərman qarşılıqlı təsirləri: Might potentiate immunosuppressants (e.g., cyclosporine).


4. Firm Introduction: Shaanxi Zhonghong Biotechnology Co., Ltd.

28-year pioneer in bioactive polysaccharide manufacturing, Shaanxi Zhonghong integrates proprietary extraction tech with international provide chain excellence to ship cGMP-grade GLPs exceeding pharmacopeial requirements.

Əsas imkanlar:

  • Patentlə qorunan hasilat: 20+ patents overlaying ultrasonic-microwave synergy (CN201810023456.7).

  • Analitik ciddilik: HPLC-ELSD, 800MHz NMR, MALDI-TOF MS making certain >99.5% təmizlik (exceeding USP/EP monographs).

  • Beynəlxalq uyğunluq: ISO 9001, FDA-GMP, EFSA, JECFA sertifikatları.

  • Zəncir ustalığını təmin edin: 80+ ölkədə soyuq zəncirli logistika.


5. Product Specs: Pharmaceutical-Grade GLP QC

Contaminant Testing Requirements

Sinif Parametr məhdudlaşdırmaq Texnikanı yoxlayın
Pestisidlər Xlorpirifos ≤0,01 ppm GC-MS/MS (AB 396/2005)
qlifosat ≤0,05 ppm HPLC-MS/MS (ISO 16308)
Ağır metallar Qurğuşun (Pb) ≤0,5 ppm ICP-MS (USP <233>)
Arsen (As) ≤0,5 ppm AAS (EP 2.4.27)
Mikrobiologiya Bütün boşqab asılıdır ≤1,000 KFU/q USP <61>
E. coli Yoxdur ISO 16654
Salmonella spp. Yoxdur FDA BAM Ch.5

6. Üstün İstehsalat İş Akışı

  1. Mənbə: Natural G. lucidum fruiting our bodies (OOP-certified).

  2. Çıxarma: Dynamic maceration (95°C, pH 6.8, 3h) → ultrafiltration (100 kDa MWCO).

  3. Deproteinization: Sevag reagent (chloroform:butanol 4:1).

  4. Təmizləmə: DEAE-Sepharose FF chromatography → lyophilization.

  5. Standartlaşdırma: Phenol-sulfuric acid assay to 40% GLP content material.


7. Sənayedə Məqsədlər

  • Nutraceuticals: Immune-boosting capsules (GLP + β-glucan synergy).

  • Reçeteli dərmanlar: Chemotherapy adjuvants (reduces cisplatin nephrotoxicity).

  • Kosmetiklər: Anti-aging serums (↑ collagen synthesis by 200%).

  • Useful Meals: Glycemic management drinks (GLP + berberine).


8. Yüksək keyfiyyətli İdarəetmə: 360° Təminat Protokolu

GLP batches bear dörd fazalı yoxlama:

  1. Şəxsiyyətin təsdiqlənməsi: FT-IR spectral match (3,400 cm⁻¹ O-H; 1,070 cm⁻¹ C-O-C).

  2. Saflığın Kəmiyyəti: HPSEC-ELSD (ICH Q2(R1)-validated; LOD: 0.05%).

  3. Bioaktivlik Testi:

    • RAW 264.7 macrophage NO manufacturing: ≥50% stimulation at 100 μg/mL

    • α-Glucosidase inhibition: IC₅₀ ≤ 2 mg/mL

  4. Sabitlik: 24-month shelf-life underneath 25°C/60% RH (ICH Q1A(R2)).


9. Sərhədlərin və Çağırışların Təhlili

  • Mexanik anlayışlar:

    • Intestine microbiota modulation (↑ Bifidobakteriya ↑ SCFA manufacturing).

    • STING pathway activation for antitumor immunity.

  • Medical Translation:

    • Part II trials for GLP-COVID-19 immunity synergy.

  • Technical Boundaries:

    • Ağızdan bioavailability: Chitosan nanoparticles to reinforce absorption from 12% to 91%.

    • Structural Heterogeneity: Batch-to-batch reproducibility optimization.

  • Davamlılıq:

    • Mycelial fermentation to preserve wild Ganoderma populations.


10. Tez-tez verilən suallar: Bacarıqlı Həllər

Q: Can GLPs change chemotherapy?
A: No. Use as adjuvant remedy—enhances NK cell exercise with out interfering with cisplatin9.

Q: Secure throughout being pregnant?
A: Restricted information. Keep away from until authorized by a doctor.

Q: Why select 40% vs 95% GLPs?
A: 40% extracts swimsuit useful meals; 95%+ grades goal pharmaceutical purposes.

S: Optimal istehlak vaxtı?
A: Morning on empty abdomen (enhances macrophage uptake).


The place to Purchase Pharmaceutical-Grade GLPs

🔬 Shaanxi Zhonghong-dan birbaşa sifariş:


Nəticə

Ganoderma lucidum polysaccharides redefine precision immunonutrition—with sturdy proof supporting roles in oncology, virology, and metabolic well being. For innovators in search of licensed, traceable GLPs, Shaanxi Zhonghong delivers unparalleled excellence: ISO 17025-accredited analytics, batch-specific HPSEC validation, and international cold-chain logistics.

Harness Reishi’s Millennium Legacy—Request Your NMR Report As we speak!


İstinadlar:

  1. Etnofarmakologiya jurnalı (2019). GLP mechanisms in most cancers apoptosis9.

  2. Karbohidrat polimerləri (2020). Structural characterization of immunomodulatory GLPs6.

  3. Yeməklər Kimyası (2021). Ultrasonic-microwave extraction optimization3.

  4. USP-NF (2023). Polysaccharide identification/purity testing tips.

  5. Frontiers in Immunology (2024). STING pathway activation by GLPs.

Ganoderma lucidum polysaccharide üçün 1 baxışı

  1. James Oli*** Avatar
    评分 4 &sol; 5

    James Oli***

    “As a health care product brand, aiherba.com’s ODM solution gives us peace of mind. They provide complete raw material traceability files. For example, the latest batch of Ganoderma lucidum triterpenoid extract can be traced from the planting to the extraction process of the organic base in Yunnan. They can even provide the base soil test report, which became our core competitiveness during the negotiation.”

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