Black Garlic S-Allyl Cysteine: The Fermented Powerhouse for Trendy Well being | Supplier & Manufacturer
1. Məhsulun təqdimatı.
Qara Sarımsaq S-Allil Sistein (SAC) əldə edilən bioaktiv orqanosulfur birləşməsidir Allium sativum by way of managed thermal fermentation. Fashioned through the transformation of white garlic into black garlic, SAC (chemical method: C₆H₁₁NO₂S) is the important thing element accountable for black garlic’s enhanced well being advantages. This water-soluble compound stands out for its antioksidant, antiinflamatuar, və kardioprotektiv xüsusiyyətlər, making it a sought-after ingredient in trendy nutraceutical and pharmaceutical purposes..
Shaanxi Zhonghong Investment Technology Co., Ltd. makes a speciality of producing SAC with exact purity ranges (5%-98%) utilizing proprietary fermentation and purification applied sciences. Our merchandise meet the best business requirements, offering a dependable supply of this bioactive compound for international well being and wellness industries.
2. Firmanın Girişi.
2.1 Main the Bioactive Compound Trade.
Shaanxi Zhonghong Investment Technology Co., Ltd yüksək texnologiyalı bir müəssisədir 28 illik təcrübə in extracting and purifying pure compounds. We combine agile R&D, collaborative innovation, and international manufacturing to ship premium plant-based elements for well being, cosmetics, and analysis sectors..
2.2 Analysis & Improvement Power.
- College Collaborations: Joint laboratories with 5 top-tier universities allow cutting-edge analysis, leading to 20+ patent kükürd birləşməsinin çıxarılması və hazırlanması üçün..
- State-of-the-Artwork Services: Outfitted with HPLC, NMR, and supercritical extraction methods, we obtain purity requirements 20% larger than business averages..
- International Community: Xidmət edir 80+ beynəlxalq məkan, we offer personalized options to multinational 药企 (pharmaceutical corporations), nutraceutical corporations, and beauty manufacturers..
3. Məhsul Təchizatı.
3.1 Botanika mənşəyi və fermentasiya.
SAC is derived from black garlic, produced by fermenting contemporary white garlic at 60–80°C for 20–90 days. This course of triggers the Maillard response, changing unstable alliin into secure SAC, with concentrations rising 10x in comparison with uncooked garlic..
3.2 Sourcing & Manufacturing Management.
- Premium Sarımsaq: Sourced from licensed organic farms in Shandong, China, and California, USA, guaranteeing low pesticide residue and excessive alliin content material..
- Fermentation Expertise: Proprietary chambers with exact temperature (±1°C) and humidity (±5% RH) management to maximise SAC biosynthesis..
4. Sağlamlığın faydaları.
4.1 Antioksidant Təhlükəsizlik.
- Mexanizm: Scavenges free radicals (e.g., hydroxyl radicals, IC50 = 8.7 μM) and prompts Nrf2-dependent antioxidant enzymes (SOD, CAT, GPx)..
- Faydaları: Reduces oxidative stress in persistent ailments, helps mobile well being, and combats age-related harm..
4.2 Cardiovascular Assist.
- Blood Strain Regulation: Inhibits angiotensin-converting enzyme (ACE), decreasing systolic blood strain by 10–15 mmHg in scientific research..
- Lipid Administration: Reduces LDL ldl cholesterol by 12–18% by way of AMPK-mediated fatty acid oxidation, enhancing vascular well being..
4.3 İmmunitetin Gücləndirilməsi.
- İmmun Hüceyrələrin Aktivləşdirilməsi: Stimulates macrophage phagocytosis and nitric oxide manufacturing, enhancing resistance to viral and bacterial infections..
- İltihab əleyhinə nəticələr: Suppresses NF-κB pathway, decreasing pro-inflammatory cytokines (TNF-α, IL-6)..
4.4 Metabolic & Liver Well being.
- Qlükoza tənzimlənməsi: Improves insulin sensitivity in skeletal muscle, useful for prediabetic people..
- Hepatoproteksiya: Reduces hepatic lipid accumulation, supporting non-alcoholic fatty liver illness (NAFLD) administration..
5. Utilization Pointers.
5.1 Ağızdan Pəhriz əlavələri.
- General Well being: 50–200 mq/gün (5%–20% SAC) kapsullarda/tabletlərdə, yemək zamanı qəbul edilir..
- Terapevtik istifadə: 500–1,000 mg/day (98% SAC) underneath medical supervision for cardiovascular or metabolic help..
5.2 Purposeful Meals & Drinks.
- Yemək komponentləri: 0.1%–0.5% powder in snacks, vitality bars, or drinks for umami taste and well being advantages..
- Formulation Ideas: Mix with vitamin C to boost SAC bioavailability by 30%..
5.3 Beauty Purposes.
- Dəriyə qulluq: 0.5%–1% in lotions/serums to spice up collagen synthesis (15% enhance) and cut back pimples irritation..
6.Qara Sarımsaq S-Allil Sistein Ehtiyatları.
6.1 Əks göstərişlər.
- Allergiya simptomları: Discontinue use if garlic allergy signs (rash, itching) happen (prevalence <0.5%)..
- Dərman qarşılıqlı təsirləri:.
- Might improve anticoagulants (e.g., warfarin); monitor INR ranges..
- Potentiates hypoglycemic medication; alter dosage with medical steering..
- Hamiləlik / Laktasiya: Restricted knowledge; seek the advice of a healthcare supplier earlier than use..
6.2 Facet Results.
Excessive doses (≥1,500 mg/day) might trigger gentle nausea or bloating in 3–5% of customers; cut back dosage if discomfort happens..
7. Məhsul Xüsusiyyətləri.
.
Undertaking.
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ad.
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Göstərici.
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Aşkarlama Texnikası.
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Pestisidlərin qalıqları.
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Xlorpirifos.
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≤ 0,01 ppm.
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GC-MS (Agilent 7890B-5977E).
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.
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Karbendazim.
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≤ 0,01 ppm.
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.
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.
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Bütün pestisidlər.
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≤ 0,1 ppm.
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.
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Ağır metallar.
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Qurğuşun (Pb).
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≤ 0,1 ppm.
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AAS (PerkinElmer PinAAcle 900T).
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.
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Arsen (As).
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≤ 0,05 ppm.
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.
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.
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Kadmium (Cd).
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≤ 0,05 ppm.
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.
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.
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Merkuri (Hg).
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≤ 0,01 ppm.
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.
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Mikrob çirklənməsi.
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Whole Viable Depend.
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≤ 100 CFU/q.
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USP <61> Microbiological Checks.
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.
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E. coli.
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Yoxdur (0/25g).
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PCR + Tradition Strategies.
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.
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Salmonella.
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Yoxdur (0/25g).
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.
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.
8. Manufacturing Course of.
8.1 Qara sarımsağın fermentasiyası.
- Uncooked Materials Choice: A dərəcəli ağ sarımsaq (alliin ≥0.8%) soyulur və sterilizasiya edilir..
- Managed Fermentation: Incubated at 65°C, 85% RH for 45 days in stainless-steel chambers to transform alliin to SAC..
- High quality Monitoring: HPLC evaluation ensures SAC focus ≥1.5% (dry weight) earlier than extraction..
8.2 Ekstraksiya və Təmizləmə.
- Solventin çıxarılması: 80% ethanol-water combination extracts SAC underneath reflux (60°C, 2 hours)..
- Filtrasiya və Xromatoqrafiya: 0.45 μm membrane filtration adopted by C18 column chromatography to realize ≥98% purity..
- Liyofilizasiya: Freeze-drying at -50°C, 0.1 mbar to protect bioactivity and kind a hygroscopic powder..
8.3 Formulation Choices.
- Pudra: 100–200 mesh, moisture ≤5%, saved in hermetic containers..
- Maye ekstraktı: 50 mg/mL in 50% ethanol, stabilized with 0.05% citric acid for beauty/useful meals use..
9. Tətbiq Ssenariləri.
9.1 Nutraceutical Ticarət.
- Cardiovascular Dietary supplements: Müstəqil SAC kapsulları (200 mq) və ya koenzim Q10 ilə qarışır..
- İmmun Yardım: Mixed with zinc and vitamin D in chewable tablets (50 mg SAC per dose)..
9.2 Purposeful Meals.
- İçkilər: Black garlic – infused drinks (100 mg SAC/250 mL) concentrating on lively shoppers..
- Pəhriz Pəhriz əlavələri: SAC-enriched protein bars for post-workout restoration..
9.3 Pharmaceutical Analysis.
- Scientific Trials: Metabolik sindrom (NCT04235678) və diabetik neyropatiya üçün tədqiq edilmişdir..
- Drug Improvement: SAC derivatives as potential ACE inhibitors for hypertension remedy..
9.4 Kosmetika.
- Anti-Growing older Merchandise: Serums with 1% SAC to enhance pores and skin elasticity and cut back wrinkle depth..
- Antioksidan Tərkiblər: UV-induksiya etdiyi oksidləşdirici stress və piqmentasiya ilə mübarizə aparan üz maskaları..
10. High quality Management Black Garlic S-Allyl Cysteine.
High quality management at Shaanxi Zhonghong ensures product integrity by way of 4 important phases:.
- Uncooked Materials Testing:.
- DNA barcoding verifies garlic species (ITS area, 99.9% accuracy)..
- HPLC quantifies alliin content material to make sure fermentation effectivity..
- Course of Monitoring:.
- IoT sensors monitor fermentation parameters (temperature, humidity) in actual time..
- Blockchain expertise data extraction/purification knowledge for full traceability..
- Purity Evaluation:.
- PDA aşkarlamalı HPLC SAC saxlama müddətini (12,5 ± 0,2 dəqiqə) və təmizliyi təsdiqləyir..
- NMR spectroscopy validates chemical construction (1H/13C NMR spectra matching USP requirements)..
- Security Testing:.
- 150+ pestisid üçün GC-MS ekranları (LOD ≤0,001 ppm)..
- Microbiological checks guarantee compliance with EP 2.6.12 and USP <62>, confirming absence of pathogens..
Every batch is accompanied by an in depth COA, guaranteeing transparency in purity (≥98% for pharmaceutical grade) and security..
11. Qablaşdırma və Logistika.
11.1 Packaging Options.
- Toplu Sifarişlər: İki qatlı PE astarlı 25 kq qida məhsulu barabanları (oksigen keçiriciliyi <10 sm³/m²/gün)..
- Pattern Orders: 1 kg aluminum foil baggage with desiccant packs (moisture absorption capability: 15g/bag)..
- Beauty Grade: İşığa həssas formulalar üçün 5 kq ultrabənövşəyi şüalara davamlı HDPE qablar..
11.2 International Logistics.
- Transport Strategies:.
- Categorical: DHL/FedEx (5–7 days to main markets), tracked by way of on-line portals..
- Sea Freight: 20–30 days with temperature-controlled containers (15–25°C) for giant orders..
- Sənədləşdirmə: COA, Halal/Kosher certificates, phytosanitary papers, and MSDS offered for all shipments..
12. Black Garlic S-Allyl Cysteine Well being Efficacy & Trade Improvements.
12.1 Mechanism of Motion.
- Ürək müdafiəsi: Inhibits vascular easy muscle cell proliferation by way of PI3K/AKT signaling..
- Antioksidləşmə: Prompts Nrf2-ARE pathway to upregulate HO-1 and NQO1, enhancing mobile redox steadiness..
12.2 Technological Developments.
- Nanokapsulyasiya: Liposomal SAC formulations enhance bioavailability by 200%, fixing water solubility points..
- Fermentasiya İnnovasiyası: Mühəndisdir Lactobacillus strains increase SAC yield by 30% by way of metabolic engineering..
12.3 Analysis Frontiers & Challenges.
- Ongoing Research:.
- Section II trial for SAC in NAFLD (ChiCTR2300078901)..
- Cognitive perform evaluation in aged populations (NCT04678901)..
- Çağırışlar:.
- Enhancing thermal stability for high-temperature meals processing..
- Standardizing analytical strategies for SAC isomer quantification..
13. Tez-tez verilən suallar.
13.1 Q: How does SAC differ from uncooked garlic compounds?.
A: SAC is a secure, odorless compound shaped throughout black garlic fermentation, with larger bioavailability and decrease pungency than uncooked garlic’s allicin..
13.2 Q: Is SAC protected for long-term use?.
A: Sure, scientific research present no adversarial results at really helpful doses (≤1,000 mg/day), with a security profile supported by 10+ years of analysis..
13.3 Q: Can SAC be utilized in toddler formulation?.
A: Not really helpful with out medical steering, as pediatric security knowledge are restricted..
13.4 Q: What’s the shelf lifetime of SAC merchandise?.
A: 24 months when saved in a cool, dry place (≤25°C, ≤60% humidity), unopened..
14. Nəticə.
Qara Sarımsaq S-Allil Sistein is a testomony to the ability of nature mixed with scientific innovation. With confirmed advantages in cardiovascular well being, immunity, and metabolism, SAC presents versatile purposes throughout nutraceutical, pharmaceutical, and beauty industries. Shaanxi Zhonghong Investment Technology Co., Ltd. delivers high-purity SAC extracts backed by 28 years of experience, guaranteeing reliability, security, and efficacy for international companions..
Bizimlə əlaqə saxlayın liaodaohai@gmail.com to discover personalized SAC options or request a pattern of our premium extracts.
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The place to Purchase Black Garlic S – Allyl Cysteine
We’re your trusted associate for sourcing high-quality Black Garlic S – Allyl Cysteine
Contact us right this moment to debate your procurement wants, request a free pattern on your R&D, and get a aggressive wholesale worth.
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E-poçt: sales@aiherba.com / liaodaohai@gmail.com
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Veb sayt: www.aiherba.com
15. İstinadlar.
- Lee, Okay. W., et al. (2012). “S-Allyl cysteine from black garlic protects in opposition to oxidative harm in PC12 cells. ” Yeməklər Kimyası, 135(3): 1446–1451..
- Kim, H. J., et al. (2016). “S-Allyl cysteine improves endothelial dysfunction by way of AMPK-dependent eNOS phosphorylation. ” Kənd təsərrüfatı və yeməklər kimyası jurnalı, 64(48): 9185–9192..
- United States Pharmacopeia (USP) 41-NF 36. “Garlic Extract High quality Requirements. “.
- Avropa Farmakopeyası 10.0. “Allium sativum L. Quru Ekstraktı üzrə monoqrafiya.”.
- ClinicalTrials.gov. "Metabolik Sindromda S-Allil Sistein" (NCT04235678).
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