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ৰেবাউডিঅ'চাইড এ

    1.ইংৰাজী নাম: Rebaudioside A

  1. নিৰ্দিষ্টকৰণ
    • বিশুদ্ধতা: Rebaudioside A ≥ 95% (HPLC); High – purity grade: ≥ 98% (HPLC)
    • কণিকাৰ আকাৰ: Standard powder ≤ 100 μm; Micronized powder ≤ 5 μm for enhanced dissolution
    • দ্ৰৱণীয়তা: Soluble in water (5 – 10 g/L at 25°C), ethanol; water – soluble formulations optimized for beverage applications
  2. ৰূপ
    • Powder: White to off – white fine powder, odorless, intensely sweet taste
  3. CAS NO.:58543-16-1
  4. লিড টাইম: ৩ – ৭ কৰ্মদিন
  5. পেকেজ
    • 1 kg/bag (aluminum foil bag), 25 kg/drum (double – layer PE bag inside cardboard drum)
  6. মূল বজাৰ: North America, Europe, Asia, South America (especially in low – calorie food and beverage industries)
  7. প্ৰয়োগৰ পৰিস্থিতি

মূল বৈশিষ্ট্যসমূহ

  • আণৱিক সূত্ৰ: C₄₄H₇₀O₂₂
  • Taste Profile: 200 – 400 times sweeter than sucrose with minimal bitter aftertaste (compared to other steviol glycosides)
  • মূল বৈশিষ্ট্যসমূহ
    • Low – Calorie Sweetener: Zero – calorie alternative to sugar, suitable for diabetic and weight – management diets.
    • Thermostability: Stable under high temperatures (up to 120°C), enabling use in baked goods and processed foods.
    • pH Stability: Remains stable across pH 3 – 9, ideal for beverages and acidic products.
    • প্ৰাকৃতিক উৎপত্তি: উলিওৱা হৈছে ষ্টেভিয়া ৰেবাউডিয়ানা leaves, meeting “clean label” consumer demands.

প্ৰয়োগৰ পৰিস্থিতি

1. খাদ্য আৰু পানীয়

  • পানীয়:
    • Added to soft drinks, juices, teas, and energy drinks at 0.01 – 0.1% concentration to replace or reduce sugar content.
    • Used in sports drinks to provide sweetness without calories, maintaining electrolyte balance.
  • Bakery & Confectionery:
    • Incorporate into cakes, cookies, and candies, maintaining texture and shelf – life while reducing sugar by 30 – 50%.
    • Ideal for sugar – free chocolate products, enhancing sweetness without affecting melting properties.
  • দুগ্ধজাত সামগ্ৰী:
    • Fortify yogurt, ice cream, and milkshakes, appealing to health – conscious consumers seeking low – calorie options.

2. খাদ্য পৰিপূৰক

  • Weight Management Formulas:
    • Capsules or powders containing Rebaudioside A combined with fiber and probiotics, marketed for appetite suppression and calorie reduction.
  • Diabetic – Friendly Supplements:
    • Included in glucose – control supplements, providing sweetness without raising blood sugar levels.

3. প্ৰসাধন সামগ্ৰী আৰু ব্যক্তিগত যত্ন

  • Oral Care:
    • Added to toothpaste, mouthwash, and chewing gum to provide sweetness while reducing sugar – related dental issues.
  • Skincare:
    • Used in lip balms and moisturizers for a sweet flavor without the risk of attracting insects (unlike sugar – based sweeteners).

4. Animal Feed

  • পোহনীয়া জন্তুৰ খাদ্য:
    • Incorporate into pet treats and kibble to enhance palatability without adding calories, beneficial for overweight pets.
  • Livestock Feed:
    • Used in poultry and swine feed to improve feed intake, potentially increasing growth efficiency.

ধৰা পেলোৱাৰ পদ্ধতি

  • উচ্চ – কাৰ্য্যক্ষমতা লিকুইড ক্ৰ'মাট'গ্ৰাফী (HPLC):
    • Column: C18 (250 × 4.6 mm, 5 μm), Mobile Phase: Acetonitrile – water (gradient elution), Flow Rate: 1.0 mL/min, Detection Wavelength: 210 nm.
  • Ultra – Performance Liquid Chromatography – Mass Spectrometry (UPLC – MS):
    • Confirms molecular structure and detects trace impurities, ensuring high – purity standards.
  • Refractive Index Detection (RID):
    • Used for quantifying Rebaudioside A in complex mixtures, providing accurate concentration data.

উৎস আৰু সুবিধা

  • প্ৰাকৃতিক উৎস: ৰ পাতৰ পৰা উলিওৱা হয় ষ্টেভিয়া ৰেবাউডিয়ানা, a plant native to South America and now cultivated globally.
  • স্থিৰতা: Renewable crop with low water requirements, supporting eco – friendly production.
  • Cost – Efficiency: Reduces long – term healthcare costs associated with sugar – related diseases (e.g., diabetes) through calorie reduction.

নিয়ন্ত্ৰণমূলক অনুসৰণ

  • আমেৰিকাৰ এফ ডি এ: Generally Recognized As Safe (GRAS) for food use since 2008, allowing inclusion in various food categories.
  • ইউৰোপীয় ইউনিয়নৰ নিয়ন্ত্ৰণ: Approved as a food additive (E960) with specific usage limits in different products.
  • চীন এনএমপিএ: Permitted as a sweetener in food and beverages, subject to national safety standards.

Rebaudioside A: The Premium Natural Sweetener Powering Healthier Formulations

1. What is Rebaudioside A?

Rebaudioside A (Reb A) is a highly prized steviol glycoside, the primary sweet-tasting compound isolated from the leaves of the ষ্টেভিয়া ৰেবাউডিয়ানা Bertoni plant. Renowned for its exceptional sweetness intensity (approximately 200-400 times sweeter than sucrose) and superior sensory profile compared to other steviol glycosides, Reb A delivers a clean, sugar-like taste with significantly reduced bitterness and lingering aftertaste. Its zero-calorie, zero-glycemic index nature makes it a cornerstone ingredient in the global shift towards natural, health-conscious sugar reduction strategies across food, beverage, and nutraceutical industries.

২) পণ্যৰ উৎস, ৰাসায়নিক ধৰ্ম আৰু মূল চিনাক্তকৰ্তা

  • উত্‍স: Extracted and purified from the leaves of the ষ্টেভিয়া ৰেবাউডিয়ানা Bertoni plant, native to South America and now cultivated globally.

  • ৰাসায়নিক ধৰ্ম:

    • Type: Diterpene glycoside.

    • আণৱিক সূত্ৰ: C₄₄H₇₀O₂₃

    • আণৱিক ওজন: 967.03 g/mol

    • CAS নম্বৰ: 58543-16-1

    • EINECS নম্বৰ: 261-342-2

    • ৰূপ: Typically a fine, white to off-white crystalline powder.

    • দ্ৰৱণীয়তা: Highly soluble in water and ethanol.

    • স্থিৰতা: Stable under high temperatures (baking, pasteurization) and across a wide pH range, making it highly versatile for processing.

3. Why Rebaudioside A is the Best & Its Health Profile

  • “The Best” & Highest Purity: Among steviol glycosides, Rebaudioside A (Reb A) is widely regarded as having the most favorable sensory profile, characterized by its clean sweetness onset and minimal bitterness/licorice aftertaste. Products labeled “High-Purity Reb A” (e.g., 95%, 97%, 98%+) contain the highest concentration of this desirable glycoside, offering superior taste performance. Reb M is also noted for a clean profile but is less abundant naturally and often more costly to produce at high purity.

  • Health Benefits & Efficacy:

    • Zero Calories & Zero Glycemic Impact: Crucial for weight management and blood sugar control, particularly beneficial for diabetics and prediabetics.

    • Dental Health: Non-cariogenic – does not promote tooth decay.

    • এন্টিঅক্সিডেন্টৰ গুণ: Some research suggests steviol glycosides possess mild antioxidant activity.

    • Blood Pressure Support: Limited studies indicate potential mild vasodilatory effects, though more research is needed for conclusive health claims.

  • Daily Intake & ADI: The Acceptable Daily Intake (ADI) for steviol glycosides (expressed as steviol equivalents) established by JECFA (FAO/WHO) and EFSA is 4 mg per kg of body weight per day. For a 70kg adult, this equates to approximately 280 mg of steviol equivalents. High-purity Reb A products typically specify their Reb A content and steviol equivalent conversion factor.

  • সুৰক্ষা আৰু পাৰ্শ্বক্ৰিয়া: Rebaudioside A is Generally Recognized As Safe (GRAS) by the US FDA and approved for food use globally (EU, JECFA, etc.). Extensive safety evaluations support its use. Potential side effects are rare but may include mild gastrointestinal discomfort (bloating, nausea) in sensitive individuals when consumed in very large quantities, significantly exceeding the ADI. No significant allergenic potential is known.

  • সাৱধানতা: While safe for the general population, individuals with severe kidney disease should consult a doctor. Always adhere to recommended usage levels in formulations.

4. Introducing Shaanxi Zhonghong Investment Technology Co., Ltd.: Your Trusted Source for Premium Reb A
Shaanxi Zhonghong Investment Technology Co., Ltd. stands as a leader in the জৈৱ সক্ৰিয় যৌগ industry, leveraging ২৮ বছৰৰ বিশেষজ্ঞতা. As a vertically integrated উচ্চ প্ৰযুক্তিৰ উদ্যোগ, we specialize in agile R&D, integrated manufacturing, and global distribution, serving the demanding needs of the chemical, materials, and life science sectors. Our core competency lies in the advanced extraction, isolation, and purification of high-value plant constituents, including premium-grade Rebaudioside A.

  • Unmatched Scientific Prowess: We maintain strategic collaborations with 5 top-tier universities মাজেদি যৌথ গৱেষণাগাৰ, driving innovation. Our technological edge is protected by over 20 patents and includes access to a proprietary global compound library.

  • অত্যাধুনিক গুণগত আন্তঃগাঁথনি: Our commitment to purity is enforced by অত্যাধুনিক বিশ্লেষণাত্মক যন্ত্ৰপাতি, সাঙুৰি High-Performance Liquid Chromatography (HPLC), Ultra-High-Performance Liquid Chromatography (UHPLC), and Superconducting Nuclear Magnetic Resonance (NMR) spectrometers. This enables us to consistently achieve purity standards exceeding industry norms by 20% or more.

  • Global Supply Chain Excellence: We possess a robust international distribution network spanning এছিয়া, ইউৰোপ, আৰু আমেৰিকা (৮০+ দেশ), প্ৰদান কৰা কাষ্টমাইজড উপাদান সমাধান to multinational pharmaceutical corporations, research institutions, and premium nutraceutical/food manufacturers.

5. Rebaudioside A Benefits: Beyond Sweetness

  • Health & Wellness: Enables significant sugar reduction without sacrificing sweetness, supporting calorie control, blood sugar management, and dental health.

  • Clean Label Appeal: A natural, plant-derived ingredient highly sought after by consumers demanding transparency.

  • Formulation Versatility: Exceptional stability under heat and across pH ranges allows use in beverages, baked goods, dairy, confectionery, and tabletop sweeteners.

  • Cost-Effectiveness: High sweetness potency means very low usage levels are required, often making it economically viable despite a higher per-kg price than sugar.

6. Using Rebaudioside A: Guidelines

  • Usage Levels: Highly potent; typical usage levels range from 0.01% to 0.05% in beverages and foods, depending on the target sweetness and the specific product matrix. Replacement levels for sucrose vary significantly.

  • সহযোগিতা: Often blended with other sweeteners (e.g., erythritol, allulose, monk fruit extract) or flavors to optimize taste profile, mask any slight aftertaste, and provide bulk.

  • Application: Easily incorporated into both aqueous and lipid-based systems. Pre-dissolving in water or a water-miscible solvent is common for uniform distribution.

7. Product Specifications: Rigorous Quality Assurance
Shaanxi Zhonghong guarantees Reb A meeting the highest international standards. Our specifications include comprehensive testing for purity, residues, heavy metals, and microbiology:

Table 1: Pesticide Residue Limits

Pesticide Residue ProjectSpecification (Max mg/kg)পৰীক্ষাৰ পদ্ধতি
এচিফেট< 0.01GC-MS, LC-MS/MS
এলড্ৰিন + ডাইলড্ৰিন< 0.01জিচি-এমএছ
BHC (α, β, γ, δ isomers)< 0.01জিচি-এমএছ
ক্ল'ৰ্ডেন (মুঠ)< 0.01জিচি-এমএছ
ডিডিটি (মুঠ)< 0.01জিচি-এমএছ
Endrin< 0.01জিচি-এমএছ
Fenvalerate< 0.01জিচি-এমএছ
Heptachlor + Epoxide< 0.01জিচি-এমএছ
হেক্সাক্ল’ৰ’বেনজিন< 0.01জিচি-এমএছ
মালাথিয়ন< 0.01জিচি-এমএছ
Methoxychlor< 0.01জিচি-এমএছ
পাৰথিয়ন< 0.01জিচি-এমএছ
পাইৰেথ্ৰিন (মুঠ)< 0.01জিচি-এমএছ

Table 2: Heavy Metal Limits

Heavy Metal ProjectSpecification (Max ppm)পৰীক্ষাৰ পদ্ধতি
আৰ্ছেনিক (As)≤ 1.0ICP-MS, USP <232>/EP 2.4.27
কেডমিয়াম (Cd)≤ 1.0ICP-MS, USP <232>/EP 2.4.27
সীহ (Pb)≤ 1.0ICP-MS, USP <232>/EP 2.4.27
বুধ (Hg)≤ 0.1ICP-MS, USP <232>/EP 2.4.27

Table 3: Microbiological Standards

Microbiological Projectনিৰ্দিষ্টকৰণপৰীক্ষাৰ পদ্ধতি
মুঠ এৰোবিক মাইক্ৰ’বায়’লজিকেল গণনা≤ ১০০০ চিএফইউ/গ্ৰামইউ এছ পি <৬১>, ই পি ২.৬.১২
মুঠ সংযুক্ত ঈষ্ট আৰু ছাঁচ≤ ১০০ চিএফইউ/গ্ৰামইউ এছ পি <৬১>, ই পি ২.৬.১২
ইস্কেৰচিয়া কলাই১০গ্ৰামত অনুপস্থিতইউ এছ পি <৬২>, ই পি ২.৬.১৩
ছালমোনেলা spp.২৫গ্ৰামত অনুপস্থিতইউ এছ পি <৬২>, ই পি ২.৬.১৩
ষ্টেফাইলোককাচ অৰেয়াছ১গ্ৰামত অনুপস্থিতইউ এছ পি <৬২>, ই পি ২.৬.১৩
ছ্যুড’ম’নাছ এৰুজিনোছা১গ্ৰামত অনুপস্থিতইউ এছ পি <৬২>, ই পি ২.৬.১৩

৮/ উন্নত উৎপাদন প্ৰক্ৰিয়া
Shaanxi Zhonghong employs a sophisticated, multi-stage cGMP-সঙ্গতিপূৰ্ণ process to ensure the highest purity Reb A:

  1. Sourcing & Pre-treatment: Selection of premium ষ্টেভিয়া ৰেবাউডিয়ানা leaves; washing, drying, and milling.

  2. নিষ্কাশন: Hot water or food-grade solvent extraction to solubilize steviol glycosides.

  3. প্ৰাথমিক বিশুদ্ধকৰণ: Filtration and centrifugation to remove insoluble plant material.

  4. Decolorization & Deionization: Removal of pigments, organic acids, and salts using activated carbon and ion-exchange resins.

  5. Advanced Chromatographic Separation: Macroporous adsorption resin chromatography and/or প্ৰস্তুতিমূলক এইচ পি এল চি are critically employed to isolate and highly purify Rebaudioside A from other glycosides (e.g., Stevioside, Reb C, Reb D).

  6. স্ফটিকীয়কৰণ: Controlled crystallization to obtain high-purity Reb A crystals.

  7. শুকুৱাই লোৱা: স্প্ৰে শুকুৱাই লোৱা অথবা ভেকুৱাম শুকুৱাই লোৱা to achieve the final powder form.

  8. মিশ্ৰণ আৰু প্ৰামাণিককৰণ: Ensuring consistent Reb A content and performance.

  9. কঠোৰ গুণগত নিয়ন্ত্ৰণ: Comprehensive analytical testing at every critical stage (HPLC, UHPLC, NMR, GC-MS, ICP-MS, microbiology).

  10. পেকেজিং: Sealed in food-grade, multi-layer moisture-barrier packaging (e.g., aluminum foil bags within cartons).

9. Key Application Scenarios

  • খাদ্য আৰু পানীয়: Soft drinks, juices, flavored waters, yogurt, ice cream, confectionery (chocolate, candies), baked goods, sauces, dressings.

  • নিউট্ৰাচিউটিকেলছ আৰু খাদ্য পৰিপূৰক: Tablets, capsules, powders, gummies for weight management, blood sugar support.

  • ফাৰ্মাচিউটিকেলছ: Sweetening agent in syrups, chewable tablets, and liquid formulations.

  • Tabletop Sweeteners: Liquid drops, sachets, and granulated blends.

  • Oral Care Products: Toothpaste, mouthwash (non-cariogenic benefit).

  • প্ৰসাধন সামগ্ৰী: Occasionally used in lip products.

10. Stringent Quality Control (QC)
Quality is paramount at Shaanxi Zhonghong. Our multi-tiered QC protocol begins with incoming raw material inspection of stevia leaves for authenticity, moisture, and initial contaminants. প্ৰক্ৰিয়াৰ ভিতৰত নিয়ন্ত্ৰণসমূহ (IPC) are rigorously applied throughout extraction, purification, chromatography, and crystallization, utilizing real-time HPLC/UHPLC monitoring to track glycoside profiles and ensure target purity levels are met before proceeding. Final product release requires full conformance testing against all specifications outlined in Section 7 (Purity by HPLC/UHPLC, Residues by GC-MS/LC-MS/MS, Heavy Metals by ICP-MS, Microbiology per USP/EP). Our cutting-edge analytical capabilities, সাঙুৰি quantitative NMR (qNMR) for absolute purity confirmation, গণ বৰ্ণালীবিজ্ঞান (MS) for structural elucidation and trace contaminant identification, and accelerated stability studies, guarantee batch-to-batch consistency, safety, and efficacy. We adhere strictly to ISO, HACCP, and cGMP principles, maintaining comprehensive documentation for full traceability.

১১) সুৰক্ষিত পেকেজিং আৰু গ্ল’বেল লজিষ্টিক

  • পেকেজিং: 1kg, 5kg, 10kg, 25kg food-grade এলুমিনিয়াম ফয়েল বেগ with HDPE inner lining, vacuum-sealed or flushed with nitrogen, placed within fiberboard drums অথবা corrugated cartons. Custom packaging available.

  • সংৰক্ষণ: ষ্ট'ৰ কৰক ক cool, dry place (<25°C, <65% RH) in original, unopened packaging. Shelf life typically 24 months.

  • লজিষ্টিক: Shipped via air freight or sea freight globally. Certificates of Analysis (CoA), Certificate of Origin (CoO), and Material Safety Data Sheet (MSDS) accompany all shipments. Compliant with international customs and food safety regulations.

12. Deep Dive: Health Mechanisms, Innovation & Research

  • স্বাস্থ্য ব্যৱস্থা: Reb A interacts with sweet taste receptors (T1R2/T1R3) on the tongue. Unlike sugar, it is not metabolized for energy in the body; it passes through unmetabolized or is metabolized by gut bacteria into steviol, which is absorbed, glucuronidated in the liver, and excreted in urine. This pathway underpins its zero-calorie status and lack of impact on blood glucose.

  • উদ্যোগ প্ৰয়োগ আৰু প্ৰযুক্তি উদ্ভাৱন: Demand drives innovation in extraction efficiency (ultrasound, microwave-assisted), purification selectivity (novel adsorbents, simulated moving bed chromatography), taste modulation (enzymatic glycosylation to create next-gen molecules like Reb D, M; blending science), and applications (improving solubility/stability in complex matrices).

  • গৱেষণাৰ সীমা আৰু প্ৰত্যাহ্বানসমূহ: Ongoing research explores metabolic effects beyond sweetness (gut microbiome modulation, anti-inflammatory potential), refined sensory prediction modelscost-effective large-scale production of minor, cleaner-tasting glycosides (Reb M, D), regulatory harmonization, and consumer education on taste perception.

13. Rebaudioside A FAQs

  • Q: Is Rebaudioside A safe? উঃ: Yes, major global health authorities (FDA, EFSA, JECFA, FSANZ) approve high-purity steviol glycosides, including Reb A, as safe for consumption within the established ADI.

  • Q: Does Reb A affect blood sugar? উঃ: No, Rebaudioside A has a zero glycemic index and does not raise blood glucose or insulin levels, making it suitable for diabetics.

  • Q: Why choose Reb A over Stevioside? উঃ: Reb A generally has a cleaner, sweeter taste profile with less bitterness and licorice aftertaste compared to Stevioside.

  • Q: Can I bake with Reb A? উঃ: Yes, Reb A is heat stable, making it suitable for baking and cooking applications.

  • Q: Are there any side effects? উঃ: Reb A is well-tolerated. Consuming amounts vastly exceeding the ADI might cause mild digestive upset in sensitive individuals, but this is uncommon at typical usage levels.

  • Q: Is Reb A natural? উঃ: Yes, it is extracted and purified directly from the Stevia leaf, qualifying as a natural sweetener.

  • Q: How is it different from artificial sweeteners? উঃ: Unlike artificial sweeteners (e.g., aspartame, sucralose), Reb A is derived from a plant source and is generally perceived more favorably by consumers seeking natural ingredients.

14. Where to Buy High-Quality Rebaudioside A?
Source premium, high-purity Rebaudioside A directly from the manufacturer, Shaanxi Zhonghong Investment Technology Co., Ltd.:

১৫) উপসংহাৰ
Rebaudioside A stands as the gold standard within the natural high-intensity sweetener market, driven by its exceptional purity, superior taste profile, zero-calorie nature, and proven safety. As consumer demand for sugar reduction and clean labels continues to surge, Reb A offers an indispensable solution for innovative food, beverage, and health product formulators. Shaanxi Zhonghong Investment Technology Co., Ltd., with its 28-year legacy, cutting-edge purification technology, unwavering commitment to quality exceeding industry benchmarks (20%+ purity advantage), and robust global supply chain, is your strategic partner for securing a reliable supply of premium-grade Rebaudioside A. Partner with us to elevate your product formulations and meet the evolving demands of the health-conscious global marketplace.

১৬) তথ্যসূত্ৰ

  1. European Food Safety Authority (EFSA). (2010). Scientific Opinion on the safety of steviol glycosides for the proposed uses as a food additive. ই এফ এছ এ জাৰ্নেল, 8(4), 1537.

  2. Food and Agriculture Organization / World Health Organization (FAO/WHO) Joint Expert Committee on Food Additives (JECFA). (2016). Specifications for Steviol Glycosides. Monograph 21.

  3. U.S. Food and Drug Administration (FDA). GRAS Notices: GRN No. 252 (Steviol Glycosides), GRN No. 732 (Reb M). [Access via FDA website].

  4. Purkayastha, S., et al. (2016). Steviol Glycosides in Commercial Stevia Products: Compositional Analysis and Their Relationship to Sweetness. কৃষি আৰু খাদ্য ৰসায়ন বিজ্ঞানৰ জাৰ্নেল, 64(4), 678–686.

  5. Ashwell, M. (2015). Stevia, Nature’s Zero-Calorie Sustainable Sweetener: A New Player in the Fight Against Obesity. Nutrition Today, 50(3), 129–134.

  6. Shankar, P., et al. (2013). Non-nutritive sweeteners: review and update. Nutrition, 29(11–12), 1293–1299. (PubMed ID: 23845273)

  7. International Stevia Council (ISC). [Industry resources & science summaries].

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