Adenine: Premium Manufacturer & Global Supplier for Pharmaceutical and Nutraceutical Applications | Aiherba
Source high-purity Adenine from Zhonghong, a leading manufacturer و مورد بالجملة. Essential nucleic acid base for pharmaceuticals and supplements. Request a free sample and get a competitive سعر يقتبس.
1. What is Adenine?
Adenine is a fundamental purine derivative, one of the four core nucleobases that form the building blocks of DNA and RNA. It is a crucial component of adenosine triphosphate (ATP), the primary energy currency of the cell, and various cofactors like NAD and FAD. Beyond its biological role, adenine is a key starting material and intermediate in the synthesis of numerous antiviral and anticancer drugs. For ب2ب clients in the pharmaceutical, nutraceutical, and research sectors, a reliable Adenine manufacturer is essential for sourcing a high-purity, compliant ingredient that meets strict quality standards for critical applications.
2. Source, Chemical Properties, and Identifiers
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Product Source: Primarily produced through chemical synthesis from simpler precursors like formamide or aminoimidazole carbonitrile (AICN) under controlled industrial conditions. This ensures high purity, consistency, and scalability.
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Chemical Classification: Purine base.
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رقم CAS: 73-24-5
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الصيغة الجزيئية (MF): C5H5N5
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الوزن الجزيئي (MW): 135.13 g/mol
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إينكس: 200-796-1
3. What Defines the Best Adenine? A B2B Buyer’s Guide
ل دولي pharmaceutical companies, supplement المصدرين, and research institutions, the “best” Adenine is defined by its ultra-high purity, low impurity profile (especially for related substances like other nucleobases), and comprehensive documentation supporting its intended use (e.g., DMF, CEP).
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المكون الرئيسي والفعالية: Premium Adenine is a synthetic compound of high purity (e.g., ≥99.0% or USP/EP grade). Its primary roles are structural and functional:
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Pharmaceutical Intermediate: A critical building block in the synthesis of nucleoside analogue drugs (e.g., Acyclovir, Tenofovir) used to treat viral infections and cancers.
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Cell Culture Media Component: Used in biopharmaceutical manufacturing as a key nutrient for cell growth and proliferation.
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Research Reagent: Essential for molecular biology research, PCR, and genetic studies.
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(Compliant for use as a pharmaceutical intermediate, in cell culture, and as a research chemical. Not typically sold as a direct dietary supplement ingredient.)
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الأصل والجودة: Our Adenine is synthesized in cGMP-compliant facilities, ensuring a product free from biological contaminants and with a consistent, well-defined chemical profile.
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Usage & Dosage:
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الاستخدام النموذجي: Incorporated as an active pharmaceutical ingredient (API) intermediate, a raw material in cell culture media, and a reagent in diagnostic kits and research laboratories.
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Recommended Dosage: There is no standard dietary dosage. All usage is highly specific to the pharmaceutical synthesis protocol, cell culture formulation, or research application.
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Applicable Audience: Pharmaceutical synthesis departments, biopharmaceutical companies, research institutions, and diagnostic kit manufacturers.
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Notes & Side Effects:
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احتياطات: FOR INDUSTRIAL AND RESEARCH USE ONLY. Not intended for direct human consumption as a dietary supplement. Handle with appropriate personal protective equipment (PPE) in a laboratory setting.
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تأثيرات جانبية: Not applicable for this B2B context. As a pharmaceutical intermediate, its safety profile is managed within the drug development process.
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4. Why Partner with Zhonghong (Aiherba) as Your Adenine Manufacturer?
Shaanxi Zhonghong Investment Technology Co., Ltd. (Global Marketing: Aiherba) is a certified high-tech enterprise and a trusted مصدر specializing in the synthesis and purification of high-value chemical and biochemical compounds for the global ب2ب سوق.
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التميز العلمي: Our joint laboratories with 5 leading universities and portfolio of 20+ patents allow us to optimize synthetic pathways for high yield, purity, and minimal environmental impact.
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Unmatched Quality Control: Our investment in advanced equipment like HPLC and Superconducting NMR ensures our purity standards meet or exceed USP, EP, and JP monograph requirements, which is critical for pharmaceutical applications.
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Global B2B Network: With 28 years of experience in fine chemicals, we supply customized ingredients and بالجملة quantities to multinational pharmaceutical corporations, بالجملة distributors, and premier research institutions across 80+ countries.
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Regulatory Support: We provide comprehensive documentation packages, including C of A, MSDS, and can support regulatory filings, making us a strategic partner for the pharmaceutical industry.
5. Detailed Product Specifications (COA)
Every batch is accompanied by a comprehensive Certificate of Analysis (COA) that confirms compliance with stringent pharmacological standards.
فئة | Item Name | مواصفة | طريقة الاختبار |
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Related Substances | HPLC Purity | ≥99.0% | كروماتوغرافيا السائل عالي الأداء |
Any Individual Impurity | ≤0.5% | كروماتوغرافيا السائل عالي الأداء | |
Total Impurities | ≤1.0% | كروماتوغرافيا السائل عالي الأداء | |
المعادن الثقيلة | الرصاص (Pb) | ≤10 mg/kg | ICP-MS / USP <231> |
الزرنيخ (As) | ≤3 mg/kg | ICP-MS | |
الكادميوم (Cd) | ≤1 mg/kg | ICP-MS | |
الزئبق (Hg) | ≤1 mg/kg | ICP-MS | |
علم الأحياء الدقيقة | إجمالي عدد اللوحات | ≤1000 وحدة تشكيل مستعمرة/جم | جامعة ساو باولو <61> |
الخميرة والعفن | ≤100 وحدة تشكيل مستعمرة/جم | جامعة ساو باولو <61> | |
الإشريكية القولونية | غائب | جامعة ساو باولو <62> | |
السالمونيلا | غائب | جامعة ساو باولو <62> | |
فحص | Adenine Content | 98.0% – 101.0% | كروماتوغرافيا السائل عالي الأداء |
خسارة عند التجفيف | ≤0.5% | جامعة جنوب المحيط الهادئ <731> |
6. Production Process & Quality Control
Our production of Adenine involves multi-step chemical synthesis from validated starting materials. The process typically begins with precursors like formamide or AICN, undergoing a series of controlled reactions (e.g., cyclization, purification) to build the purine ring structure. The crude product is then purified through techniques such as recrystallization from a suitable solvent or chromatography to achieve the desired pharmaceutical-grade purity. The final product is dried and milled to a consistent particle size if required.
ملكنا ضبط الجودة is exceptionally rigorous and designed for pharmaceutical intermediates. It starts with qualifying all raw materials. In-process controls (IPC) are implemented at critical steps to monitor reaction completion and impurity profiles. The final product undergoes exhaustive testing. كروماتوغرافيا السائل عالية الأداء (HPLC) with UV detection is the primary method for quantifying the Adenine content and profiling related substances and impurities. ICP-MS is used for sensitive heavy metal detection. معايرة كارل فيشر precisely measures water content. Additionally, we perform microbiological testing to ensure bioburden limits are met. This multi-tiered QC protocol, conducted in our state-of-the-art labs, guarantees a product that is consistent, pure, and suitable for its demanding applications.
7. سيناريوهات التطبيق
Adenine is a critical ingredient for advanced industries:
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المستحضرات الصيدلانية: Primarily used as a key intermediate in the synthesis of a wide range of antiviral and anticancer nucleoside analogue drugs.
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Biopharmaceuticals: An essential component of defined cell culture media used in the production of monoclonal antibodies, vaccines, and other biologics.
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Molecular Biology & Diagnostics: Used as a raw material in PCR kits, nucleotide synthesis, and various research reagents.
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Chemical Research: Serves as a building block for novel chemical entities and materials science research.
8. Technical Role, Research, and Innovation
Adenine’s role is structural and functional, serving as a core scaffold in nucleic acids and critical biomolecules. The main research frontier involves developing more efficient and greener synthetic routes for its production and creating novel derivatives with enhanced biological activities. The key challenge for manufacturers is achieving and consistently maintaining ultra-high purity with minimal isomeric and other purine impurities, which is crucial for pharmaceutical efficacy and safety. At Zhonghong, our ابتكار lies in our patented, optimized synthesis pathways that maximize yield and purity while reducing environmental impact, providing our ب2ب partners with a reliable and high-quality building block for their most important products.
9. FAQ – Frequently Asked Questions
Q: What is the Minimum Order Quantity (MOQ) for pharmaceutical grade?
A: MOQs vary based on the specific grade and packaging. We cater to both large-scale بالجملة orders for production and smaller R&D quantities. Contact us for details.
Q: Can you provide Adenine that complies with USP/EP/JP monographs?
A: Yes, we can supply Adenine that meets the specifications of various international pharmacopoeias. Please specify your required standard when inquiring.
Q: Do you offer custom synthesis for Adenine derivatives?
A: Yes, we specialize in customized herbal extract and chemical solutions. Our R&D team can collaborate on the synthesis of specific purine derivatives. Inquire for feasibility.
Q: Do you offer samples for our quality testing and R&D?
A: Absolutely. We provide free sample materials to qualified businesses and research institutions for evaluation and testing purposes.
Q: What documentation do you provide for pharmaceutical customers?
A: We provide a comprehensive suite including Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), and can provide supporting data for Drug Master Files (DMF) as required.
10. Where to Buy and Request Free Samples
As a leading manufacturer و global supplier of fine chemicals and pharmaceutical intermediates, we are your trusted partner for sourcing high-purity Adenine.
Contact us today to discuss your procurement needs, request a free sample for your QA/QC, and get a competitive wholesale price.
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بريد إلكتروني: sales@aiherba.com / liaodaohai@gmail.com
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موقع إلكتروني: www.aiherba.com
11. الخاتمة
ل ب2ب clients in the pharmaceutical and life science industries, Adenine is a fundamental, non-negotiable building block. Choosing a supplier with robust synthetic capabilities, uncompromising quality control aligned with pharmacopoeial standards, and proven دولي regulatory support is paramount. Zhonghong (Aiherba) provides not just a chemical, but a reliable partnership, offering a premium, thoroughly documented product that integrates seamlessly into your critical workflows, backed by decades of experience in chemical manufacturing.
12. المراجع
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USP/EP/JP Monographs for Adenine.
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Journal of Medicinal Chemistry: Studies on the synthesis and application of purine derivatives in drug discovery.
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Organic Process Research & Development: Publications on the industrial synthesis and optimization of nucleobases.
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ICH Guidelines (Q3A, Q7) for impurities in new drug substances and Good Manufacturing Practice.
المراجعات
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