مسحوق الكولاجين السمكي النقي

Pure Fish Collagen Powder: Premium Marine Sourcing from Zhonghong Biotech (Free Samples Available)

1. What is Pure Fish Collagen Powder?
Pure Fish Collagen Powder, predominantly Type I collagen, is a hydrolyzed protein derived from the skin, scales, and bones of marine fish (e.g., Tilapia, Cod). This enzymatic hydrolysis process yields bioactive ببتيدات الكولاجين – low molecular weight fragments (typically 2,000-5,000 Da) with significantly enhanced التوافر البيولوجي compared to native collagen. These peptides are rapidly absorbed into the bloodstream via the paracellular pathway و PepT1 transporter, facilitating targeted delivery to skin, joints, and connective tissues to stimulate endogenous collagen synthesis via fibroblast activation and modulation of TGF-β/Smad signaling pathways. Its superior solubility, neutral taste, and odorless profile make it ideal for nutraceutical and functional food applications.

2. مصدر المنتج والخصائص الكيميائية والتعريف

• مصدر: Sustainably sourced Marine Fish (Tilapia nilotica, Gadus morhua). Traceability protocols ensure origin compliance.

• رقم CAS: 9007-34-5

• الصيغة الجزيئية (MF): Represents repeating amino acid sequences (primarily Gly-X-Y, where X & Y are often Pro and Hyp).

• الوزن الجزيئي (MW): Hydrolyzed form: Typically 2,000 – 5,000 Daltons (Da).

• إينكس: 232-697-4

• الخصائص الكيميائية الرئيسية: High solubility (><｜begin▁of▁thinking｜> pH stability, rich in Glycine (~33%), Proline (~12%), Hydroxyproline (~10%) – crucial for triple-helix stability and biological activity. Exhibits characteristic FT-IR spectra (Amide I, II, III bands) and DSC thermograms.

3. Why Zhonghong Biotech’s Pure Fish Collagen is the Optimal Choice
Zhonghong Biotech sets the benchmark for premium Pure Fish Collagen Powder through rigorous science and quality:

• Premium Ingredients: 100% pure hydrolyzed fish collagen peptides. Non-GMO, Gluten-Free, Allergen-Free (BSE/TSE Free). No fillers or artificial additives.

• Clinically Validated Efficacy (Compliant): Supports skin dermal matrix integrity (increases elasticity, reduces wrinkles – in vivo studies), promotes chondrocyte proliferation و synovial fluid viscosity for joint comfort, enhances bone mineral density (Osteoblast stimulation), aids muscle protein synthesis (MPS), and supports gut mucosal barrier function.

• Optimal Daily Intake: Recommended dosage: 5g to 10g daily. Efficacy supported by clinical research (e.g., Proksch et al., 2014). Consult a physician for specific needs.

• المنشأ والتصنيع: Sourced responsibly, processed in cGMP-certified facilities in China. Advanced enzymatic hydrolysis ensures optimal peptide profile.

• الاستخدام: Easily soluble in hot/cold beverages, smoothies, yogurts, or baked goods. Ideal for capsules, tablets, and functional foods.

• الجمهور المستهدف: Adults seeking skin health, joint support, athletes, seniors, individuals in wellness programs.

• السلامة والآثار الجانبية: Generally Recognized As Safe (GRAS). Well-tolerated. Potential mild gastrointestinal discomfort if taken in excessive doses initially.

• اعتبارات حاسمة: Verify بيانات مسببات الحساسية (fish source), ensure product has full شهادة التحليل (CoA) confirming purity and safety (see below). Contraindicated for individuals with severe fish allergies.

4. Zhonghong Biotech: Your Trusted Collagen Partner
Zhonghong Biotech (Shaanxi Zhonghong Investment Technology Co., Ltd.) is a globally recognized leader in the research, development, and large-scale manufacturing (Bulk Supplier) of high-purity bioactive compounds. With 28 سنة of expertise in استخراج النباتات و marine bioactives, we serve the chemical, material science, and life science sectors.

• البراعة العلمية: Collaboration with 5 جامعات النخبة fuels our أكثر من 20 تقنية حاصلة على براءة اختراع and exclusive المكتبة العالمية المركبة, creating significant R&D barriers.

• البنية التحتية المتطورة: مجهزة بـ HPLC (الكروماتوغرافيا السائلة عالية الأداء), UHPLC-MS (Ultra-HPLC-Mass Spectrometry)، و 600MHz Superconducting NMR (Nuclear Magnetic Resonance). Our purity standards exceed industry norms by 20%+.

• التميز في سلسلة التوريد العالمية: Our robust network delivers مستخلص عشبي مخصص and bioactive solutions to أكثر من 80 دولة, serving multinational pharmaceutical companies, leading nutraceutical brands (بالجملة partners), and premier research institutions. We specialize in حلول مخصصة tailored to specific application requirements.

5. Comprehensive Product Specifications & Certificate of Analysis (CoA)
Zhonghong guarantees transparency. Every batch undergoes stringent testing per international pharmacopeia (USP, EP).

Pure Fish Collagen Powder – Certificate of Analysis (CoA) Summary

6. Advanced Production Process: Precision Hydrolysis
Our optimized manufacturing ensures peak bioactivity:

1. Sustainable Sourcing & Prep: Raw fish by-products undergo rigorous veterinary inspection and controlled trimming/washing.

2. Demineralization & Defatting: Acid/alkali treatment removes minerals and lipids.

3. Enzymatic Hydrolysis: Specific proteolytic enzymes (e.g., Alcalase, Trypsin) cleave collagen under controlled T/pH/duration to yield target peptide profiles (<5kDa).

4. التنقية متعددة المراحل: Filtration (ultrafiltration/nanofiltration), ion-exchange, and activated carbon remove impurities, odors, and salts.

5. التعقيم والتجفيف: Terminal sterilization (where applicable) followed by التجفيف بالرش (inlet/outlet temp control) or التجميد بالتجفيف لتحقيق أقصى قدر من الاستقرار.

6. Strict QC Release: Comprehensive testing per CoA specifications before packaging.

7. سيناريوهات تطبيق متنوعة

• المواد المغذية: Capsules, tablets, stick packs, gummies for skin beauty, joint health, sports nutrition.

• الأطعمة والمشروبات الوظيفية: Fortified protein drinks, dairy products, health bars, confectionery.

• مستحضرات التجميل: Key active in anti-aging serums, creams, masks for dermal rejuvenation و moisture retention.

• Medical Nutrition: Supports tissue repair and wound healing formulations.

• Pet Nutrition: Joint and coat health supplements.

8. Rigorous Quality Control (QC) Protocol
Zhonghong’s QC is integrated throughout the product lifecycle. Starting from متوافق مع ممارسات التصنيع الجيدة (GMP) raw material qualification (vendor audits, CoA review), we implement Process Analytical Technology (PAT) for real-time monitoring of critical parameters (pH, temp, peptide size via GPC/SEC) during hydrolysis. Our state-of-the-art Quality Control Laboratory، مجهزة بـ HPLC-DAD/ELSD/RID, ICP-MS, كروماتوغرافيا الغاز-مطياف الكتلة/مطياف الكتلة, UHPLC-QTOF-MS، و Microbiological suites, performs identity, purity, potency, and safety testing per validated methods aligned with ICH Q2(R1). Stability studies (ICH Q1A) ensure shelf-life. إمكانية تتبع الدفعات is enforced. Our ايزو 9001:2015 و ISO 22000/FSSC 22000 certified systems guarantee consistent, safe, high-quality مسحوق الكولاجين السمكي النقي meeting global regulatory standards (FDA, EFSA, Health Canada).

9. التعبئة والتغليف الآمن والخدمات اللوجستية العالمية

• التغليف: Available in multi-layer foil bags (1kg, 5kg, 10kg) with desiccant, inside food-grade براميل البولي إيثيلين عالي الكثافة (25kg) or طبول الألياف (20kg). Custom packaging for حجم كبير orders. Nitrogen flushing optional.

• تخزين: Store in a cool (<25°C), dry place. Shelf life: 24 months unopened.

• الخدمات اللوجستية: Efficient global shipping via air/sea freight. Expertise in export documentation and cold chain (if required). Compliant with IATA/IMDG regulations.

10. Deep Dive: Health Mechanisms, Applications & Innovation

• آليات الصحة: Bioactive peptides (e.g., Pro-Hyp, Gly-Pro-Hyp) act as ligands for receptors on fibroblasts/chondrocytes, stimulating collagen I/III, elastin، و hyaluronic acid synthesis عبر MAPK/ERK و PI3K/Akt pathways. Exhibit مضاد للأكسدة activity (radical scavenging), MMP inhibition, and modulate inflammatory cytokines (e.g., TNF-α, IL-1β).

• تطبيقات الصناعة: قيادة الابتكار في beauty-from-within supplements, osteoarthritis management, sarcopenia mitigation, wound healing biomaterials، و functional food fortification.

• Research & Challenges: Current focus on structure-activity relationship (SAR) of specific peptides, bioavailability enhancement (nano-delivery), sustainable sourcing (by-product valorization), and clinical validation for new indications (gut-brain axis, metabolic health). Challenges include standardization of bioactive peptide profiles and large-scale cost-effective production of specific sequences.

11. الأسئلة الشائعة
Q1: What makes marine collagen better than bovine/porcine?
A1: Marine collagen (Type I) boasts superior التوافر البيولوجي due to lower molecular weight peptides and is preferred for ethical/religious (halal/kosher potential) and safety (BSE-free) reasons. Often perceived as more sustainable.
Q2: How long to see results?
A2: Clinical studies show visible skin improvements (hydration, elasticity) often within 4-8 أسابيع of consistent use (5-10g/day). Joint benefits may take 8-12 أسبوعًا.
Q3: Is it safe during pregnancy/breastfeeding?
A3: Generally safe, but consult your physician before starting any new supplement.
Q4: Can vegetarians/vegans use this?
A4: No, as it’s derived from fish. Plant-based collagen boosters exist but do not provide direct collagen peptides.
Q5: Do you offer free samples?
A5: Yes! We provide عينة مجانية من مستخلص الأعشاب of our Pure Fish Collagen Powder for qualified businesses. Contact us to request.
Q6: What customization options are available?
A6: نحن نقدم مستخلص عشبي مخصص solutions including specific peptide profiles (molecular weight distribution), flavor masking, instantization, and blends with other actives (e.g., Vitamin C, Hyaluronic Acid). Discuss your customized needs.
Q7: What is the minimum order quantity (MOQ)?
A7: Competitive MOQs for حجم كبير و بالجملة quantities. Contact sales for specific details based on your requirements.
Q8: Where can I buy?
A8: Contact Zhonghong Biotech directly for حجم كبير, بالجملة، و الشركة المصنعة للمعدات الأصلية inquiries. Visit our website for more information.

12. Where to Buy & Request Free Samples
Ready to source premium مسحوق الكولاجين السمكي النقي? As a leading الشركة المصنعة و مزود, Zhonghong Biotech offers competitive الأسعار ل حجم كبير quantities and بالجملة partnerships.

• Get Your Free Sample: Experience the Zhonghong quality difference. Qualified businesses can request عينة مجانية من مستخلص الأعشاب.

• اتصل بنا:

  • بريد إلكتروني: sales@aiherba.com, liaodaohai@gmail.com

  • موقع إلكتروني: www.aiherba.com

  • Inquiry Focus: Bulk Orders, Wholesale Pricing, Customization, Free Samples, OEM/ODM Services.

13. الخاتمة
مسحوق الكولاجين السمكي النقي represents a scientifically substantiated bioactive ingredient for enhancing skin, joint, and overall connective tissue health. تشونغهونغ للتكنولوجيا الحيوية الروافع المالية 28 سنة of expertise in bioactive extraction and purification, cutting-edge analytical technology (HPLC, NMR, MS), and a global distribution network to deliver a premium, high-purity, traceable marine collagen peptide product. Our commitment to ضبط الجودة exceeding industry standards, التخصيص capabilities, and provision of عينات مجانية establishes us as the trusted partner for nutraceutical brands, functional food developers, and بالجملة distributors worldwide. Contact us today to discuss your collagen sourcing needs and explore partnership opportunities.

14. المراجع

1. Proksch, E., et al. (2014). Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: A double-blind, placebo-controlled study. علم الأدوية وعلم وظائف الأعضاء الجلدية, 27(1), 47-55.

2. León-López, A., et al. (2019). Hydrolyzed Collagen—Sources and Applications. الجزيئات, 24(22), 4031.

3. Khatri, M., et al. (2021). The effects of collagen peptide supplementation on body composition, collagen synthesis, and recovery from joint injury and exercise: a systematic review. الأحماض الأمينية, 53(10), 1493-1506.

4. Song, H., et al. (2022). Bioactive collagen peptides: a review of their generation, bioactivities and applications. مجلة الأغذية الوظيفية, 88, 104909.

5. ISO 3496:1994. Animal and vegetable fats and oils — Determination of hydroxyproline content.

6. USP-NF General Chapters: <61> Microbiological Examination, <232> Elemental Impurities, <561> Articles of Botanical Origin, <197> Spectrophotometric Identification Tests.

7. European Pharmacopoeia (Ph. Eur.) Monographs and General Chapters (e.g., 2.4.8 Heavy metals, 2.6.12/13 Microbiological examination).