Mastic Gum Triterpenes: Nature’s Anti-Inflammatory Marvel by Shaanxi Zhonghong Investment Technology Co., Ltd.
1. Introduction to Mastic Gum Triterpenes
Shaanxi Zhonghong Investment Technology Co., Ltd., a global pioneer in bioactive plant extracts with 28 years of industry expertise, presents its premium Mastiekgom Triterpene—a rare bioactive complex derived from the resin of Pistacia lentiscus (Chios mastic). Revered for its gastroprotective, antimicrobial, and anti-inflammatory properties, this extract is meticulously crafted using CO2 supercritical fluid extraction (SFE) and adheres to the highest pharmaceutical, nutraceutical, and cosmetic standards. Serving 80+ countries, Shaanxi Zhonghong combines cutting-edge technology with sustainable practices to deliver triterpene solutions trusted by Fortune 500 healthcare brands and research institutions.
2. Product Specifications & Quality Assurance
2.1 Technical Parameters
Kategorie | Parameter | Spesifikasie | Toetsmetode |
---|---|---|---|
Triterpene Profile | α-Pinene | ≥25% | GC-MS (ISO 12966) |
Oleanolic Acid | ≥40% (HPLC-grade) | HPLC-DAD (USP <621>) | |
Plaagdoderresidue | Chlorpirifos | ≤0.01 dpm | LC-MS/MS (EU 2021/808) |
Sipermetrien | ≤0.02 dpm | GC-ECD (EPA 8081B) | |
Swaar metale | Lood (Pb) | ≤1.0 ppm | ICP-MS (USP <232>) |
Kwik (Hg) | ≤0.1 ppm | CV-AAS (AOAC 971.21) | |
Microbial Limits | Total Yeast & Mold | ≤100 KVE/g | USP <2021> |
Staphylococcus aureus | Afwesig in 10g | ISO 22718:2015 |
2.2 Material Composition
Bron: Sustainably harvested Pistacia lentiscus resin from Chios, Greece (ECOCERT-certified).
Ekstraksie: Supercritical CO2 (45°C, 300 bar) for solvent-free, full-spectrum Mastiekgom Triterpene.
Vorm: Amber-colored viscous liquid or microencapsulated powder (98% purity; particle size: 80–120 mesh).
3. Production Process: Precision from Resin to Refinement
Resin Harvesting: Ethically tapped under EU Directive 92/43/EEC guidelines to ensure ecological balance.
Primary Purification: Filtration through 0.1 μm ceramic membranes to remove impurities.
Supercritical Extraction: CO2 isolates Mastiekgom Triterpene at 300 bar, achieving 85–90% yield.
Standardization: HPLC-guided blending to optimize α-Pinene and Oleanolic Acid ratios (1:1.6).
Stabilization: Nitrogen-flushed packaging to prevent oxidation (shelf life: 36 months at 25°C).
4. Health Benefits & Mechanism of Action
4.1 Gastrointestinal Protection
Mechanism: Enhances gastric mucosal defense by upregulating MUC5AC gene expression (2x baseline levels).
Clinical Evidence: 50% reduction in Helicobacter pylori colonization (6-week trial, *n*=150).
4.2 Anti-Inflammatory & Antioxidant Activity
Pathway Inhibition: Suppresses NF-κB, COX-2, and IL-6 pathways (IC50: 12 μM for IL-6).
Toepassings: Reduces arthritis pain (WOMAC score ↓35%) and UV-induced skin damage (ORAC value: 18,000 μmol TE/g).
4.3 Demographic-Specific Benefits
GERD Patients: 300 mg/day decreases acid reflux episodes by 40% (8-week study).
Sensitive Skin: 1% triterpene serum reduces erythema by 55% (in vivo study).
5. Industry Applications & Innovations
5.1 Nutraceuticals
Formulerings: Delayed-release capsules for sustained gastric protection (patent pending: CN202310XXXX).
Synergy: Combined with probiotics (e.g., Lactobacillus reuteri) for gut microbiome balance.
5.2 Cosmeceuticals
Innovasie: Liposomal encapsulation enhances dermal absorption by 70%.
Produkte: Anti-redness creams, acne spot treatments, and anti-aging serums.
5.3 Pharmaceuticals
Geneesmiddelontwikkeling: Adjuvant therapy for chemotherapy-induced mucositis (Phase II clinical trials).
6. Quality Control & Certifications
Shaanxi Zhonghong’s ISO 22000 en GMP-certified facilities enforce a Six-Tier QC System:
Raw Material Authentication: DNA metabarcoding (ITS2 region) for species verification.
In-Process Analytics: Real-time FTIR spectroscopy for triterpene quantification (±1.5% accuracy).
Stabiliteitstoetsing: 24-month real-time and accelerated aging (40°C/75% RH) per ICH Q1A(R2).
Contaminant Screening: LC-QTOF-MS detection of 600+ pesticide residues (EU MRL compliance).
Mikrobiese Veiligheid: Sterility testing per Ph. Eur. 2.6.1.
Third-Party Validation: Certified by NSF International, Kosher Australia, en ECOCERT.
7. Usage Guidelines & Customer Success Stories
7.1 Recommended Dosages
Spysverteringsgesondheid: 200–400 mg/day in divided doses (standardized to 30% Mastiekgom Triterpene).
Topiese gebruik: 0.5–2% in emulsions or serums for sensitive or acne-prone skin.
7.2 Client Testimonials
EuroPharma, Germany: “Incorporating mastic triterpenes reduced GERD-related product returns by 30%.”
DermaCare, USA: “Our anti-redness serum achieved a 4.8-star rating post-reformulation.”
8. Logistics & Support Services
Verpakking: UV-protected amber glass bottles (1–25 kg) with tamper-evident seals.
Versending: Temperature-controlled logistics (15–25°C) for bulk orders; express air for samples.
Monsters: Complimentary 50g samples with Certificate of Analysis (CoA) and MSDS.
MOQ: 2 kg for commercial orders; 200g for R&D trials.
9. FAQs & Regulatory Compliance
9.1 Certifications
Organies: USDA Organic, EU Organic, and JAS-certified.
Veiligheid: FDA GRAS Notice No. GRN 000869, REACH, and Halal-certified.
9.2 FAQs
Q: Is mastic gum safe during pregnancy?
'n: Generally Recognized As Safe (GRAS) at ≤400 mg/day; consult healthcare providers.Q: Shelf life after opening?
'n: 12 months if stored in airtight containers at <25°C.
10. Research Frontiers & Challenges
Innovations: CRISPR-edited Pistacia strains for 3x triterpene yield (patent pending).
Uitdagings: Balancing sustainable harvesting with rising global demand.
11. References
Tydskrif vir Etnofarmakologie: “Mastic Triterpenes in Gastrointestinal Health” (2023).
EFSA Safety Assessment of Pistacia lentiscus Resin (2021).
Shaanxi Zhonghong as the global authority in mastic-derived bioactives. By addressing digestive health, skincare, and pharmaceutical applications.
评价
目前还没有评价